CHEBI:61176 - eletriptan hydrobromide

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ChEBI Name eletriptan hydrobromide
ChEBI ID CHEBI:61176
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C22H27BrN2O2S
Net Charge 0
Average Mass 463.43100
Monoisotopic Mass 462.09766
InChI InChI=1S/C22H26N2O2S.BrH/c1-24-12-5-6-19(24)15-18-16-23-22-10-9-17(14-21(18)22)11-13-27(25,26)20-7-3-2-4-8-20;/h2-4,7-10,14,16,19,23H,5-6,11-13,15H2,1H3;1H/t19-;/m1./s1
InChIKey UTINOWOSWSPFLJ-FSRHSHDFSA-N
SMILES Br.CN1CCC[C@@H]1Cc1c[nH]c2ccc(CCS(=O)(=O)c3ccccc3)cc12
Roles Classification
Biological Role(s): serotonergic agonist
An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
Application(s): serotonergic agonist
An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
vasoconstrictor agent
Drug used to cause constriction of the blood vessels.
non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing eletriptan hydrobromide (CHEBI:61176) has part eletriptan(1+) (CHEBI:61177)
eletriptan hydrobromide (CHEBI:61176) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
eletriptan hydrobromide (CHEBI:61176) has role serotonergic agonist (CHEBI:35941)
eletriptan hydrobromide (CHEBI:61176) has role vasoconstrictor agent (CHEBI:50514)
eletriptan hydrobromide (CHEBI:61176) is a hydrobromide (CHEBI:48367)
IUPAC Name
5-[2-(phenylsulfonyl)ethyl]-3-[(2R)-pyrrolidin-2-ylmethyl]-1H-indole hydrobromide
Synonyms Sources
(R)-3-((1-methyl-2-pyrrolidinyl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole monohydrobromide ChemIDplus
eletriptan monohydrobromide ChEBI
Brand Name Source
RELPAX ChEBI
Manual Xrefs Databases
D01973 KEGG DRUG
DB00216 DrugBank
View more database links
Registry Numbers Types Sources
177834-92-3 CAS Registry Number KEGG DRUG
177834-92-3 CAS Registry Number ChemIDplus
8459649 Reaxys Registry Number Reaxys
Last Modified
02 February 2011
General Comment
2011-02-02 A selective serotonin (5HT1) agonist, eletriptan hydrobromide is used for acute treatment of the headache phase of migraine attacks.