CHEBI:135859 - efonidipine

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ChEBI Name efonidipine
ChEBI ID CHEBI:135859
Definition A racemate comprising of equimolar amounts of (R)- and (S)-efonidipine. It is a antihypertensive drug and a dual T-type and L-type calcium channel blocker.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C34H38N3O7P
Net Charge 0
Average Mass 631.666
Monoisotopic Mass 631.24474
Roles Classification
Biological Role(s): calcium channel blocker
One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
Application(s): antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
vasodilator agent
A drug used to cause dilation of the blood vessels.
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ChEBI Ontology
Outgoing efonidipine (CHEBI:135859) has part (R)-efonidipine (CHEBI:146219)
efonidipine (CHEBI:135859) has part (S)-efonidipine (CHEBI:146220)
efonidipine (CHEBI:135859) has role antihypertensive agent (CHEBI:35674)
efonidipine (CHEBI:135859) has role calcium channel blocker (CHEBI:38215)
efonidipine (CHEBI:135859) has role vasodilator agent (CHEBI:35620)
efonidipine (CHEBI:135859) is a racemate (CHEBI:60911)
IUPAC Name
rac-2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate
INNs Sources
éfonidipine WHO MedNet
efonidipine WHO MedNet
efonidipino WHO MedNet
efonidipinum WHO MedNet
Synonyms Sources
(±)-efonidipine ChEBI
NZ-105 DrugBank
NZ105 ChEBI
rac-efonidipine ChEBI
racemic efonidipine ChEBI
Manual Xrefs Databases
992 DrugCentral
D07886 KEGG DRUG
DB09235 DrugBank
Efonidipine Wikipedia
View more database links
Registry Number Type Source
111011-63-3 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
25 February 2020