doxapram hydrochloride monohydrate (CHEBI:31520)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	doxapram hydrochloride monohydrate

ChEBI ID	CHEBI:31520

Definition	The monohydrate form of doxapram hydrochloride. A central and respiratory stimulant with a brief duration of action, it is used as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

more structures >>

Formula

C24H33ClN2O3

Net Charge

Average Mass

432.98300

Monoisotopic Mass

432.21797

InChI

InChI=1S/C24H30N2O2.ClH.H2O/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21;;/h3-12,22H,2,13-19H2,1H3;1H;1H2

InChIKey

ZOMBFZRWMLIDPX-UHFFFAOYSA-N

SMILES

O.[Cl-].CCN1CC(CC[NH+]2CCOCC2)C(C1=O)(c1ccccc1)c1ccccc1

Roles Classification
Application(s):	central nervous system stimulant Any drug that enhances the activity of the central nervous system.

ChEBI Ontology
Outgoing	doxapram hydrochloride monohydrate (CHEBI:31520) has part doxapram hydrochloride (anhydrous) (CHEBI:59837) doxapram hydrochloride monohydrate (CHEBI:31520) has role central nervous system stimulant (CHEBI:35337) doxapram hydrochloride monohydrate (CHEBI:31520) is a hydrate (CHEBI:35505)

IUPAC Name

4-[2-(1-ethyl-5-oxo-4,4-diphenylpyrrolidin-3-yl)ethyl]morpholin-4-ium chloride—water (1/1)

Synonyms	Sources
(±±)-1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone monohydrochloride monohydrate	ChemIDplus
(±)-doxapram hydrochloride monohydrate	ChEBI
1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one hydrochloride hydrate	ChEBI
1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one hydrochloride monohydrate	ChEBI
1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one hydrochloride—water (1/1)	ChEBI
Doxapram hydrochloride	KEGG COMPOUND
doxapram hydrochloride hydrate	ChemIDplus
Doxapram hydrochloride monohydrate	KEGG COMPOUND

Last Modified

23 July 2010