A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
(R)-temafloxacin
(CHEBI:77794)
has role
antibacterial drug
(CHEBI:36047)
(R)-temafloxacin
(CHEBI:77794)
has role
antiinfective agent
(CHEBI:35441)
(R)-temafloxacin
(CHEBI:77794)
has role
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
(CHEBI:50750)
(R)-temafloxacin
(CHEBI:77794)
is a
1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
(CHEBI:77796)
(R)-temafloxacin
(CHEBI:77794)
is enantiomer of
(S)-temafloxacin
(CHEBI:77795)