CHEBI:27965 - conessine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name conessine
ChEBI ID CHEBI:27965
Definition A steroid alkaloid that is con-5-enine substituted by a N,N-dimethylamino group at position 3. It has been isolated from the plant species of the family Apocynaceae.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:3853, CHEBI:23369
Supplier Information
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formulae C24H40N2
C24H40N2
Net Charge 0
Average Mass 356.58780
Monoisotopic Mass 356.31915
InChI InChI=1S/C24H40N2/c1-16-20-8-9-22-19-7-6-17-14-18(25(3)4)10-12-23(17,2)21(19)11-13-24(20,22)15-26(16)5/h6,16,18-22H,7-15H2,1-5H3/t16-,18-,19+,20+,21-,22-,23-,24-/m0/s1
InChIKey GPLGAQQQNWMVMM-MYAJQUOBSA-N
SMILES C[C@H]1[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@H](CC[C@]5(C)[C@H]4CC[C@]23CN1C)N(C)C
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): H3-receptor antagonist
A histamine antagonist that selectively binds to but does not activate histamine H3 receptors, thereby blocking the actions of endogenous histamine.
antimalarial
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
antibacterial agent
A substance (or active part thereof) that kills or slows the growth of bacteria.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
Application(s): H3-receptor antagonist
A histamine antagonist that selectively binds to but does not activate histamine H3 receptors, thereby blocking the actions of endogenous histamine.
antimalarial
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing conessine (CHEBI:27965) has functional parent conanine (CHEBI:35655)
conessine (CHEBI:27965) has role antibacterial agent (CHEBI:33282)
conessine (CHEBI:27965) has role antimalarial (CHEBI:38068)
conessine (CHEBI:27965) has role H3-receptor antagonist (CHEBI:64176)
conessine (CHEBI:27965) has role plant metabolite (CHEBI:76924)
conessine (CHEBI:27965) is a steroid alkaloid (CHEBI:26767)
conessine (CHEBI:27965) is a tertiary amino compound (CHEBI:50996)
IUPAC Name
N,N-dimethylcon-5-enin-3β-amine
Synonyms Sources
Conessine KEGG COMPOUND
Conessinum ChemIDplus
Neriine ChemIDplus
Roquessine ChemIDplus
Manual Xrefs Databases
C00002243 KNApSAcK
C06545 KEGG COMPOUND
Conessine Wikipedia
View more database links
Registry Numbers Types Sources
4702160 Beilstein Registry Number Beilstein
4702160 Reaxys Registry Number Reaxys
546-06-5 CAS Registry Number KEGG COMPOUND
546-06-5 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
15413865 PubMed citation Europe PMC
18683917 PubMed citation Europe PMC
20161899 PubMed citation Europe PMC
21834632 PubMed citation Europe PMC
23758861 PubMed citation Europe PMC
Last Modified
28 July 2014