|
soulattrolide |
|
CHEBI:66516 |
|
A member of the class of coumarins that is 11,12-dihydro-2H,6H,10H-dipyrano[2,3-f:2',3'-h]chromen-2-one substituted by a phenyl group at position 4, methyl groups at positions 6, 6, 10 and 11 and a hydroxy group at position 12 (the 10S,11R,12S stereoisomer). Isolated from Calophyllum brasiliense and Calophyllum soulattri, it exhibits anti-HIV activity. |
|
This entity has been manually annotated by the ChEBI Team.
|
|
|
|
Molfile
XML
SDF
|
|
|
|
InChI=1S/C25H24O5/c1-13-14(2)28-22-16-10-11-25(3,4)30-23(16)19-17(15-8-6-5-7-9-15)12-18(26)29-24(19)20(22)21(13)27/h5-14,21,27H,1-4H3/t13-,14-,21-/m0/s1 |
BXENDTPSKAICGV-RXSFTSLZSA-N |
C[C@@H]1Oc2c3C=CC(C)(C)Oc3c3c(cc(=O)oc3c2[C@@H](O)[C@H]1C)-c1ccccc1 |
|
Calophyllum brasiliense
(IPNI:427115-1)
|
Found in
leaf
(BTO:0000713).
See:
PubMed
|
Calophyllum soulattri
(NCBI:txid257776)
|
Found in
bark
(BTO:0001301).
See:
DOI
|
Calophyllum teysmannii
(NCBI:txid667334)
|
Found in
latex
(BTO:0000710).
See:
PubMed
|
HIV-1 reverse transcriptase inhibitor
An entity which inhibits the activity of HIV-1 reverse transcriptase.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
|
|
View more via ChEBI Ontology
(10S,11R,12S)-12-hydroxy-6,6,10,11-tetramethyl-4-phenyl-11,12-dihydro-2H,6H,10H-dipyrano[2,3-f:2',3'-h]chromen-2-one
|
(10α,11β,12β)-(−)-11,12-dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-phenyl-2H,6H,10H-benzo(1,2-b:3,4-b':5,6-b'')tripyran-2-one
|
ChemIDplus
|
1443041
|
Reaxys Registry Number
|
Reaxys
|
65025-62-9
|
CAS Registry Number
|
ChemIDplus
|
15340243
|
PubMed citation
|
Europe PMC
|
7506311
|
PubMed citation
|
Europe PMC
|
8864237
|
PubMed citation
|
Europe PMC
|
|