CHEBI:180502 - chlorprothixene hydrochloride

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ChEBI Name chlorprothixene hydrochloride
ChEBI ID CHEBI:180502
Definition The hydrochloride salt of chlorprothixene.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C18H18ClNS.ClH
Net Charge 0
Average Mass 352.320
Monoisotopic Mass 351.06153
InChI InChI=1S/C18H18ClNS.ClH/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18;/h3-4,6-10,12H,5,11H2,1-2H3;1H
InChIKey YWKRLOSRDGPEJR-UHFFFAOYSA-N
SMILES Cl.[H]C(CCN(C)C)=C1C2=CC(Cl)=CC=C2SC2=C1C=CC=C2
Roles Classification
Biological Role(s): cholinergic antagonist
Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Application(s): geroprotector
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
antiemetic
A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.
cholinergic antagonist
Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
first generation antipsychotic
Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
sedative
A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing chlorprothixene hydrochloride (CHEBI:180502) has part chlorprothixene(1+) (CHEBI:180503)
chlorprothixene hydrochloride (CHEBI:180502) has role antiemetic (CHEBI:50919)
chlorprothixene hydrochloride (CHEBI:180502) has role cholinergic antagonist (CHEBI:48873)
chlorprothixene hydrochloride (CHEBI:180502) has role dopaminergic antagonist (CHEBI:48561)
chlorprothixene hydrochloride (CHEBI:180502) has role first generation antipsychotic (CHEBI:65190)
chlorprothixene hydrochloride (CHEBI:180502) has role geroprotector (CHEBI:176497)
chlorprothixene hydrochloride (CHEBI:180502) has role non-narcotic analgesic (CHEBI:35481)
chlorprothixene hydrochloride (CHEBI:180502) has role sedative (CHEBI:35717)
chlorprothixene hydrochloride (CHEBI:180502) is a hydrochloride (CHEBI:36807)
IUPAC Name
3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine hydrochloride
Synonyms Sources
2-chloro-9-(3-dimethylaminopropylidene)thioxanthene hydrochloride ChEBI
3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine—hydrogen chloride IUPAC
3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-aminium chloride IUPAC
chlorprothixene HCl ChEBI
Manual Xrefs Databases
20479320 ChemSpider
DBSALT002973 DrugBank
View more database links
Citations Waiting for Citations Types Sources
16751116 PubMed citation Europe PMC
24134630 PubMed citation Europe PMC
Last Modified
23 September 2021