CHEBI:134703 - fluciclovine (18F)

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ChEBI Name fluciclovine (18F)
ChEBI ID CHEBI:134703
ChEBI ASCII Name fluciclovine ((18)F)
Definition A member of the class of cyclobutanes that is cyclobutane which carries a carboxy, amino and (18F)fluoro groups at positions 1, 1 and 3, respectively (the 1r,3r-stereoisomer). It is a positron emission tomography (PET) radiotracer for visualizing prostate cancer.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C5H8[18F]NO2
Net Charge 0
Average Mass 132.125
Monoisotopic Mass 132.05644
InChI InChI=1S/C5H8FNO2/c6-3-1-5(7,2-3)4(8)9/h3H,1-2,7H2,(H,8,9)/t3-,5-/i6-1
InChIKey NTEDWGYJNHZKQW-DGMDOPGDSA-N
SMILES N[C@]1(C[C@H]([18F])C1)C(O)=O
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Application(s): radioactive imaging agent

radiopharmaceutical
Any pharmaceutical compound containing a radioisotope.
(via (18)F radiopharmaceutical )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing fluciclovine (18F) (CHEBI:134703) has role radioactive imaging agent (CHEBI:37336)
fluciclovine (18F) (CHEBI:134703) is a α-amino acid (CHEBI:33704)
fluciclovine (18F) (CHEBI:134703) is a 18F radiopharmaceutical (CHEBI:49127)
fluciclovine (18F) (CHEBI:134703) is a cyclobutanes (CHEBI:156473)
fluciclovine (18F) (CHEBI:134703) is a fluoroamino acid (CHEBI:24068)
fluciclovine (18F) (CHEBI:134703) is a monocarboxylic acid (CHEBI:25384)
fluciclovine (18F) (CHEBI:134703) is a primary amino compound (CHEBI:50994)
IUPAC Name
(1r,3r)-1-amino-3-(18F)fluorocyclobutanecarboxylic acid
INNs Sources
fluciclovina (18F) WHO MedNet
fluciclovine (18F) WHO MedNet
fluciclovine (18F) WHO MedNet
fluciclovinum (18F) WHO MedNet
Synonyms Sources
(18F)FACBC DrugBank
(18F)GE-148 DrugBank
(1r,3r)-1-amino-3-(18F)fluorocyclobutane-1-carboxylic acid IUPAC
18F-FACBC ChEBI
18F-fluciclovine ChEBI
anti-(18)F-FACBC ChEBI
anti-(18F)FABC ChemIDplus
anti-1-amino-3-18F-flurocyclobutane-1-carboxylic acid ChemIDplus
anti-3[18F]FACBC ChEBI
anti-[18F]FACBC ChEBI
Axumin KEGG DRUG
FACBC F-18 DrugBank
fluciclovine F 18 DrugBank
fluciclovine F-18 ChemIDplus
fluciclovine F18 ChemIDplus
GE-148 DrugCentral
Ge-148 (18F) ChemIDplus
Ge-148 F-18 ChemIDplus
NMK 36 ChemIDplus
NMK-36 ChemIDplus
NMK36 ChemIDplus
trans-1-amino-3-[18F]fluorocyclobutanecarboxylic acid ChEBI
Manual Xrefs Databases
23313216 ChemSpider
5153 DrugCentral
D10860 KEGG DRUG
DB13146 DrugBank
EP2793954 Patent
Fluciclovine_(18F) Wikipedia
GB2561122 Patent
US10967077 Patent
WO2011044410 Patent
WO2014023775 Patent
View more database links
Registry Number Type Source
222727-39-1 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
15 June 2021