fludiazepam (CHEBI:31618)

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ChEBI Name	fludiazepam

ChEBI ID	CHEBI:31618

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C16H12ClFN2O

Net Charge

Average Mass

302.73046

Monoisotopic Mass

302.06222

InChI

InChI=1S/C16H12ClFN2O/c1-20-14-7-6-10(17)8-12(14)16(19-9-15(20)21)11-4-2-3-5-13(11)18/h2-8H,9H2,1H3

InChIKey

ROYOYTLGDLIGBX-UHFFFAOYSA-N

SMILES

CN1C(=O)CN=C(c2ccccc2F)c2cc(Cl)ccc12

Roles Classification
Biological Role(s):	GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via benzodiazepine )

Application(s):	anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. (via benzodiazepine )

ChEBI Ontology
Outgoing	fludiazepam (CHEBI:31618) has functional parent diazepam (CHEBI:49575) fludiazepam (CHEBI:31618) has functional parent monofluorobenzene (CHEBI:5115) fludiazepam (CHEBI:31618) has role anxiolytic drug (CHEBI:35474) fludiazepam (CHEBI:31618) is a 1,4-benzodiazepinone (CHEBI:35500) fludiazepam (CHEBI:31618) is a organochlorine compound (CHEBI:36683) fludiazepam (CHEBI:31618) is a organofluorine compound (CHEBI:37143)

IUPAC Name

7-chloro-5-(2-fluorophenyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one

Synonyms	Sources
7-chloro-5-(o-Fluorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one	NIST Chemistry WebBook
Erispan	NIST Chemistry WebBook
fludiazepam	ChemIDplus

Last Modified

22 February 2017