CHEBI:60791 - lidocaine hydrochloride monohydrate

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ChEBI Name lidocaine hydrochloride monohydrate
ChEBI ID CHEBI:60791
Definition The monohydrate form of lidocaine hydrochloride.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C14H25ClN2O2
Net Charge 0
Average Mass 288.81400
Monoisotopic Mass 288.16046
InChI InChI=1S/C14H22N2O.ClH.H2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H;1H2
InChIKey YECIFGHRMFEPJK-UHFFFAOYSA-N
SMILES O.[Cl-].CC[NH+](CC)CC(=O)Nc1c(C)cccc1C
Roles Classification
Application(s): local anaesthetic
Any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block.
anti-arrhythmia drug
A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
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ChEBI Ontology
Outgoing lidocaine hydrochloride monohydrate (CHEBI:60791) has part lidocaine hydrochloride (CHEBI:50512)
lidocaine hydrochloride monohydrate (CHEBI:60791) has role anti-arrhythmia drug (CHEBI:38070)
lidocaine hydrochloride monohydrate (CHEBI:60791) has role local anaesthetic (CHEBI:36333)
lidocaine hydrochloride monohydrate (CHEBI:60791) is a hydrate (CHEBI:35505)
IUPAC Name
N-(2,6-dimethylphenyl)-N2,N2-diethylglycinamide hydrochloride—water (1/1)
Synonyms Sources
2-(diethylamino)-2',6'-acetoxylidide monohydrochloride monohydrate ChemIDplus
2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide monohydrochloride monohydrate ChEBI
diethylaminoacet-2,6-xylidide hydrochloride monohydrate ChemIDplus
lidocaine hydrochloride ChemIDplus
Brand Name Source
Xylocard ChEBI
Manual Xrefs Databases
D08127 KEGG DRUG
DB00281 DrugBank
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Registry Numbers Types Sources
18845016 Reaxys Registry Number Reaxys
6108-05-0 CAS Registry Number KEGG DRUG
6108-05-0 CAS Registry Number ChemIDplus
Last Modified
09 December 2010
General Comment
2010-12-08 Both the anhydrous and the monohydrate forms of lidocaine hydrochloride are used as local anaesthetics, as well as for treatment of ventricular arrhythmias, especially after myocardial infarction.