CHEBI:5091 - flecainide acetate

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ChEBI Name flecainide acetate
ChEBI ID CHEBI:5091
Definition An acetate salt obtained by combining flecainide with one molar equivalent of acetic acid. An antiarrhythmic agent used to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:76029
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Formulae C17H20F6N2O3.C2H4O2
C19H24F6N2O5
Net Charge 0
Average Mass 474.39470
Monoisotopic Mass 474.15894
InChI InChI=1S/C17H20F6N2O3.C2H4O2/c18-16(19,20)9-27-12-4-5-14(28-10-17(21,22)23)13(7-12)15(26)25-8-11-3-1-2-6-24-11;1-2(3)4/h4-5,7,11,24H,1-3,6,8-10H2,(H,25,26);1H3,(H,3,4)
InChIKey RKXNZRPQSOPPRN-UHFFFAOYSA-N
SMILES CC(O)=O.FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)C(=O)NCC1CCCCN1
Roles Classification
Application(s): anti-arrhythmia drug
A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
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ChEBI Ontology
Outgoing flecainide acetate (CHEBI:5091) has part flecainide(1+) (CHEBI:76033)
flecainide acetate (CHEBI:5091) has role anti-arrhythmia drug (CHEBI:38070)
flecainide acetate (CHEBI:5091) is a acetate salt (CHEBI:59230)
IUPAC Names
2-({[2,5-bis(2,2,2-trifluoroethoxy)benzoyl]amino}methyl)piperidinium acetate
N-(piperidin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide acetate
Synonyms Sources
flecainide monoacetate ChEBI
N-(Piperidin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide monoacetate ChemIDplus
R 818 ChemIDplus
R-818 ChemIDplus
Brand Name Source
Tambocor KEGG DRUG
Manual Xrefs Databases
D00638 KEGG DRUG
DB01195 DrugBank
EP1918280 Patent
EP2359814 Patent
Flecainide Wikipedia
WO2011098194 Patent
View more database links
Registry Numbers Types Sources
4119882 Reaxys Registry Number Reaxys
54143-56-5 CAS Registry Number ChemIDplus
54143-56-5 CAS Registry Number KEGG DRUG
Citations Waiting for Citations Types Sources
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Last Modified
23 October 2013