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(2R*,3R*)- 2,3- dihydro- 7- hydroxy- 2,3- dimethyl- 2- [4,8- dimethyl- 3(E)- 7- nonadien- 6- onyl]furo[3,2- c]coumarin |
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CHEBI:65928 |
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(2R*,3R*)- 2,3- dihydro- 7- hydroxy- 2,3- dimethyl- 2- [4,8- dimethyl- 3(E)- 7- nonadien- 6- onyl]furo[3,2- c]coumarin |
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A furanocoumarin that is 2,3-dihydrofuro[3,2-c]coumarin substituted by a hydroxy group at position 7, methyl groups at positions 2 and 3 (relatively trans configuration) and a 4,8-dimethyl-3(E)-7-nonadien-6-onyl moiety at position 2. Isolated from the roots of Ferula fukanensis, it exhibits inhibitory effect on the production of nitric oxide (NO). |
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![](images/goldenstar.gif) ![](images/goldenstar.gif)
This entity has been manually annotated by the ChEBI Team.
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Molfile
XML
SDF
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InChI=1S/C24H28O5/c1- 14(2) 11- 18(26) 12- 15(3) 7- 6- 10- 24(5) 16(4) 21- 22(29- 24) 19- 9- 8- 17(25) 13- 20(19) 28- 23(21) 27/h7- 9,11,13,16,25H,6,10,12H2,1- 5H3/b15- 7+/t16- ,24- /m1/s1 |
VFFCJVAKVAWFMA-BAFNZYHESA-N |
C[C@@H]1c2c(O[C@]1(C)CC\C=C(/C)CC(=O)C=C(C)C)c1ccc(O)cc1oc2=O |
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Ferula fukanensis
(IPNI:842281-1)
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Found in
root
(BTO:0001188).
See:
PubMed
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EC 1.14.13.39 (nitric oxide synthase) inhibitor
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of nitric oxide synthase (EC 1.14.13.39).
(via (2R*,3R*)-2,3-dihydro-7-hydroxy-2,3-dimethyl-2-[4,8-dimethyl-3(E)-7-nonadien-6-onyl]furo[3,2-c]coumarin )
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via (2R*,3R*)-2,3-dihydro-7-hydroxy-2,3-dimethyl-2-[4,8-dimethyl-3(E)-7-nonadien-6-onyl]furo[3,2-c]coumarin )
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View more via ChEBI Ontology
Outgoing
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(2R*,3R*)- 2,3- dihydro- 7- hydroxy- 2,3- dimethyl- 2- [4,8- dimethyl- 3(E)- 7- nonadien- 6- onyl]furo[3,2- c]coumarin
(CHEBI:65928)
has role
EC 1.14.13.39 (nitric oxide synthase) inhibitor
(CHEBI:61908)
(2R*,3R*)- 2,3- dihydro- 7- hydroxy- 2,3- dimethyl- 2- [4,8- dimethyl- 3(E)- 7- nonadien- 6- onyl]furo[3,2- c]coumarin
(CHEBI:65928)
has role
metabolite
(CHEBI:25212)
(2R*,3R*)- 2,3- dihydro- 7- hydroxy- 2,3- dimethyl- 2- [4,8- dimethyl- 3(E)- 7- nonadien- 6- onyl]furo[3,2- c]coumarin
(CHEBI:65928)
is a
furanocoumarin
(CHEBI:24128)
(2R*,3R*)- 2,3- dihydro- 7- hydroxy- 2,3- dimethyl- 2- [4,8- dimethyl- 3(E)- 7- nonadien- 6- onyl]furo[3,2- c]coumarin
(CHEBI:65928)
is a
ketone
(CHEBI:17087)
(2R*,3R*)- 2,3- dihydro- 7- hydroxy- 2,3- dimethyl- 2- [4,8- dimethyl- 3(E)- 7- nonadien- 6- onyl]furo[3,2- c]coumarin
(CHEBI:65928)
is a
phenols
(CHEBI:33853)
(2R*,3R*)- 2,3- dihydro- 7- hydroxy- 2,3- dimethyl- 2- [4,8- dimethyl- 3(E)- 7- nonadien- 6- onyl]furo[3,2- c]coumarin
(CHEBI:65928)
is a
sesquiterpenoid
(CHEBI:26658)
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(2R*,3R*)- 2- [(3E)- 4,8- dimethyl- 6- oxonona- 3,7- dien- 1- yl]- 7- hydroxy- 2,3- dimethyl- 2,3- dihydro- 4H- furo[3,2- c]chromen- 4- one
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15043424
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PubMed citation
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Europe PMC
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