CHEBI:64115 - (1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin hydrochloride

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ChEBI Name (1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin hydrochloride
ChEBI ID CHEBI:64115
ChEBI ASCII Name (1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin hydrochloride
Definition A hydrochloride obtained by reaction of (1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin with one equivalent of hydrochloric acid. Dopamine receptor antagonist with preferential action at presynaptic receptors (pKi values are 6.95, 6.67, 6.37, 6.21 and 6.07 at hD3. hD4, hD2S, hD2L and rD2 receptors respectively).
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C15H24ClNO
Net Charge 0
Average Mass 269.81000
Monoisotopic Mass 269.15464
InChI InChI=1S/C15H23NO.ClH/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3;/h5-7,11,14,16H,4,8-10H2,1-3H3;1H/t11-,14+;/m0./s1
InChIKey KIRYNZFMOLYYQB-YECZQDJWSA-N
SMILES Cl.CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C
Roles Classification
Biological Role(s): dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
Application(s): dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
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ChEBI Ontology
Outgoing (1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin hydrochloride (CHEBI:64115) has part (1S,2R)-5-methoxy-1-methyl-2-(propylammonio)tetralin(1+) (CHEBI:64118)
(1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin hydrochloride (CHEBI:64115) has role dopaminergic antagonist (CHEBI:48561)
(1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin hydrochloride (CHEBI:64115) is a hydrochloride (CHEBI:36807)
IUPAC Name
(1S,2R)-5-methoxy-1-methyl-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride
Synonyms Sources
(+)-AJ 76 hydrochloride ChEBI
(1S,2R)-5-methoxy-1-methyl-N-propyl-1,2,3,4-tetrahydronaphthalen-2-aminium chloride IUPAC
cis-(+)-5-methoxy-1-methyl-2-(propylamino)tetralin hydrochloride ChEBI
Registry Number Type Source
6076657 Reaxys Registry Number Reaxys
Last Modified
07 March 2012