InChI=1S/C25H38O5/c1- 6- 25(4,5) 24(28) 30- 21- 12- 15(2) 11- 17- 8- 7- 16(3) 20(23(17) 21) 10- 9- 19- 13- 18(26) 14- 22(27) 29- 19/h7- 8,11,15- 16,18- 21,23,26H,6,9- 10,12- 14H2,1- 5H3/t15- ,16- ,18+,19+,20- ,21- ,23- /m0/s1 |
RYMZZMVNJRMUDD-HGQWONQESA-N |
CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 |
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EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor
An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of anthrax lethal factor endopeptidase (EC 3.4.24.83).
EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor
Any EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme.
(via statin )
ferroptosis inducer
Any substance that induces or promotes ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.
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prodrug
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
geroprotector
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
anticholesteremic drug
A substance used to lower plasma cholesterol levels.
(via statin )
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View more via ChEBI Ontology
(1S,3R,7S,8S,8aR)- 8- {2- [(2R,4R)- 4- hydroxy- 6- oxotetrahydro- 2H- pyran- 2- yl]ethyl}- 3,7- dimethyl- 1,2,3,7,8,8a- hexahydronaphthalen- 1- yl 2,2- dimethylbutanoate
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2,2- dimethylbutyric acid, 8- ester with (4R,6R)- 6- (2- ((1S,2S,6R,8S,8aR)- 1,2,6,7,8,8a- hexahydro- 8- hydroxy- 2,6- dimethyl- 1- naphthyl)ethyl)tetrahydro- 4- hydroxy- 2H- pyran- 2- one
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ChemIDplus
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MK-733
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KEGG DRUG
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Simvastatin
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KEGG DRUG
|
Simvastatina
|
ChemIDplus
|
Simvastatine
|
ChemIDplus
|
Simvastatinum
|
ChemIDplus
|
Zocor
|
ChemIDplus
|
4768037
|
Beilstein Registry Number
|
Beilstein
|
79902-63-9
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CAS Registry Number
|
KEGG DRUG
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79902-63-9
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CAS Registry Number
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ChemIDplus
|
11336576
|
PubMed citation
|
Europe PMC
|
12827636
|
PubMed citation
|
Europe PMC
|
14561068
|
PubMed citation
|
Europe PMC
|
14691614
|
PubMed citation
|
Europe PMC
|
14973129
|
PubMed citation
|
Europe PMC
|
16144183
|
PubMed citation
|
Europe PMC
|
17640385
|
PubMed citation
|
Europe PMC
|
18199328
|
PubMed citation
|
Europe PMC
|
18688862
|
PubMed citation
|
Europe PMC
|
18936176
|
PubMed citation
|
Europe PMC
|
22737247
|
PubMed citation
|
Europe PMC
|
|