favipiravir (CHEBI:134722)

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ChEBI Name	favipiravir

ChEBI ID	CHEBI:134722

Definition	A member of the class of pyrazines that is pyrazine substituted by aminocarbonyl, hydroxy and fluoro groups at positions 2, 3 and 6, respectively. It is an anti-viral agent that inhibits RNA-dependent RNA polymerase of several RNA viruses and is approved for the treatment of influenza in Japan.

Stars	This entity has been manually annotated by the ChEBI Team.

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Formula

C5H4FN3O2

Net Charge

Average Mass

157.104

Monoisotopic Mass

157.02875

InChI

InChI=1S/C5H4FN3O2/c6-2-1-8-5(11)3(9-2)4(7)10/h1H,(H2,7,10)(H,8,11)

InChIKey

ZCGNOVWYSGBHAU-UHFFFAOYSA-N

SMILES

NC(=O)C1=NC(F)=CN=C1O

Roles Classification
Biological Role(s):	antiviral drug A substance used in the prophylaxis or therapy of virus diseases. anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor A DNA polymerase inhibitor that interferes with the action of a RNA-directed RNA polymerase (EC 2.7.7.48).

Application(s):	antiviral drug A substance used in the prophylaxis or therapy of virus diseases.

ChEBI Ontology
Outgoing	favipiravir (CHEBI:134722) has role anticoronaviral agent (CHEBI:149553) favipiravir (CHEBI:134722) has role antiviral drug (CHEBI:36044) favipiravir (CHEBI:134722) has role EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor (CHEBI:170010) favipiravir (CHEBI:134722) is a hydroxypyrazine (CHEBI:71633) favipiravir (CHEBI:134722) is a organofluorine compound (CHEBI:37143) favipiravir (CHEBI:134722) is a primary carboxamide (CHEBI:140324)

Incoming	favipiravir-RTP (CHEBI:170009) has functional parent favipiravir (CHEBI:134722)

IUPAC Name

6-fluoro-3-hydroxypyrazine-2-carboxamide

Synonyms	Sources
6-fluoro-3-hydroxy-2-pyrazinecarboxamide	ChemIDplus
fapilavir	DrugBank
T 705	ChemIDplus
T-705	ChemIDplus
T705	ChemIDplus

Last Modified

26 April 2021