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> Main
CHEBI:68847 - azilsartan kamedoxomil
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ChEBI Name
azilsartan kamedoxomil
ChEBI ID
CHEBI:68847
Definition
An organic potassium salt that is the monopotassium salt of azilsartan medoxomil. A prodrug for azilsartan, it is used for treatment of hypertension.
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This entity has been manually annotated by the ChEBI Team.
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Formula
C30H23KN4O8
Net Charge
0
Average Mass
606.62390
Monoisotopic Mass
606.11530
InChI
InChI=1S/C30H24N4O8.K/c1-
3-
38-
28-
31-
23-
10-
6-
9-
22(27(35)
39-
16-
24-
17(2)
40-
30(37)
41-
24)
25(23)
34(28)
15-
18-
11-
13-
19(14-
12-
18)
20-
7-
4-
5-
8-
21(20)
26-
32-
29(36)
42-
33-
26;/h4-
14H,3,15-
16H2,1-
2H3,(H,32,33,36)
;/q;+1/p-
1
InChIKey
IHWFKDWIUSZLCJ-UHFFFAOYSA-M
SMILES
[K+].CCOc1nc2cccc(C(=O)OCc3oc(=O)oc3C)c2n1Cc1ccc(cc1)-c1ccccc1-c1noc(=O)[n-]1
Roles Classification
Biological Role
(s):
angiotensin receptor antagonist
A hormone antagonist that blocks angiotensin receptors.
Application
(s):
prodrug
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
angiotensin receptor antagonist
A hormone antagonist that blocks angiotensin receptors.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
azilsartan kamedoxomil (
CHEBI:68847
)
has part
azilsartan medoxomil(1−) (
CHEBI:68849
)
azilsartan kamedoxomil (
CHEBI:68847
)
has role
angiotensin receptor antagonist (
CHEBI:61016
)
azilsartan kamedoxomil (
CHEBI:68847
)
has role
antihypertensive agent (
CHEBI:35674
)
azilsartan kamedoxomil (
CHEBI:68847
)
has role
prodrug (
CHEBI:50266
)
azilsartan kamedoxomil (
CHEBI:68847
)
is a
organic potassium salt (
CHEBI:50394
)
IUPAC Name
potassium 3-
{4'-
[(2-
ethoxy-
7-
{[(5-
methyl-
2-
oxo-
1,3-
dioxol-
4-
yl)methoxy]carbonyl}-
1
H
-
benzimidazol-
1-
yl)methyl]biphenyl-
2-
yl}-
5-
oxo-
1,2,4-
oxadiazol-
4-
ide
Synonym
Source
TAK-491
ChemIDplus
Brand Name
Source
Edarbi
KEGG DRUG
Manual Xrefs
Databases
D08865
KEGG DRUG
US2005187269
Patent
WO2012107814
Patent
View more database links
Registry Numbers
Types
Sources
12331024
Reaxys Registry Number
Reaxys
863031-24-7
CAS Registry Number
KEGG DRUG
Last Modified
15 November 2012