CHEBI:231355 - tasquinimod

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ChEBI Name tasquinimod
ChEBI ID CHEBI:231355
Definition Tasquinimod is a quinoline-3-carboxamide linomide analogue with antiangiogenic and potential antineoplastic activities. Tasquinimod has been shown to decrease blood vessel density but the exact mechanism of action is not known. This agent has also been shown to augment the antineoplastic effects of docetaxel and androgen ablation in a murine model of prostate cancer involving human prostate cancer xenografts.
Stars This entity has been manually annotated by a third party.
Submitter Delphine Zhou
Supplier Information
Download Molfile XML SDF
Formula C20H17F3N2O4
Net Charge 0
Average Mass 406.361
Monoisotopic Mass 406.11404
InChI InChI=1S/C20H17F3N2O4/c1-24(12-9-7-11(8-10-12)20(21,22)23)18(27)16-17(26)15-13(25(2)19(16)28)5-4-6-14(15)29-3/h4-10,26H,1-3H3
InChIKey ONDYALNGTUAJDX-UHFFFAOYSA-N
SMILES CN1C2=C(C(=CC=C2)OC)C(=C(C1=O)C(=O)N(C)C3=CC=C(C=C3)C(F)(F)F)O
ChEBI Ontology
Outgoing tasquinimod (CHEBI:231355) is a organic molecular entity (CHEBI:50860)
Synonym Source
ABR-215050 SUBMITTER
Registry Number Type Source
254964-60-8 CAS Registry Number SUBMITTER