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ChEBI
> Main
CHEBI:66118 - jaspamide P
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ChEBI Name
jaspamide P
ChEBI ID
CHEBI:66118
Definition
A cyclodepsipeptide isolated from
Jaspis splendens
. A derivative of jaspamide, it has been shown to exhibit cytotoxic and microfilament disruption activity.
Stars
This entity has been manually annotated by the ChEBI Team.
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Formula
C37H48N4O9
Net Charge
0
Average Mass
692.79840
Monoisotopic Mass
692.34213
InChI
InChI=1S/C37H48N4O9/c1-
21-
16-
22(2)
18-
24(4)
49-
32(43)
19-
30(26-
12-
14-
27(42)
15-
13-
26)
39-
34(45)
31(41(6)
35(46)
25(5)
38-
33(44)
23(3)
17-
21)
20-
37(48-
7)
28-
10-
8-
9-
11-
29(28)
40-
36(47)
50-
37/h8-
16,22-
25,30-
31,42H,17-
20H2,1-
7H3,(H,38,44)
(H,39,45)
(H,40,47)
/b21-
16+/t22-
,23-
,24-
,25-
,30+,31?,37?/m0/s1
InChIKey
FOEVCQQBKHZRMA-YSCUOIDASA-N
SMILES
COC1(CC2N(C)
C(=O)
[C@H]
(C)
NC(=O)
[C@@H]
(C)
C\C(C)
=C\[C@H]
(C)
C[C@H]
(C)
OC(=O)
C[C@@H]
(NC2=O)
c2ccc(O)
cc2)
OC(=O)
Nc2ccccc12
Metabolite of Species
Details
Jaspis
sp.
endens
(WORMS:169842)
See:
DOI
Roles Classification
Chemical Role
(s):
Bronsted base
A molecular entity capable of accepting a hydron from a donor (Br
o
nsted acid).
(via
organic amino compound
)
Biological Role
(s):
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
actin polymerisation inhibitor
Any substance that inhibits the polymerisation of the protein actin.
Application
(s):
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
jaspamide P (
CHEBI:66118
)
has role
actin polymerisation inhibitor (
CHEBI:70728
)
jaspamide P (
CHEBI:66118
)
has role
antineoplastic agent (
CHEBI:35610
)
jaspamide P (
CHEBI:66118
)
has role
metabolite (
CHEBI:25212
)
jaspamide P (
CHEBI:66118
)
is a
cyclodepsipeptide (
CHEBI:35213
)
jaspamide P (
CHEBI:66118
)
is a
ether (
CHEBI:25698
)
jaspamide P (
CHEBI:66118
)
is a
macrocycle (
CHEBI:51026
)
IUPAC Name
(4
R
,10
S
,13
S
,15
E
,17
R
,19
S
)-
4-
(4-
hydroxyphenyl)-
7-
[(4-
methoxy-
2-
oxo-
1,4-
dihydro-
2
H
-
3,1-
benzoxazin-
4-
yl)methyl]-
8,10,13,15,17,19-
hexamethyl-
1-
oxa-
5,8,11-
triazacyclononadec-
15-
ene-
2,6,9,12-
tetrone
Registry Number
Type
Source
18837689
Reaxys Registry Number
Reaxys
Last Modified
14 March 2013
General Comment
2013-03-14
Tetrahedron
(2009), 65, 51-56.