buzepide (CHEBI:157619)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	buzepide

ChEBI ID	CHEBI:157619

Definition	A member of the class of azepanes that is 2-phenylacetamide in which the methylene hydrogens at position 2 are replaced by a phenyl group and an aminocarbonyl group. It inhibits gastric juice secretion.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C22H28N2O

Net Charge

Average Mass

336.479

Monoisotopic Mass

336.22016

InChI

InChI=1S/C22H28N2O/c23-21(25)22(19-11-5-3-6-12-19,20-13-7-4-8-14-20)15-18-24-16-9-1-2-10-17-24/h3-8,11-14H,1-2,9-10,15-18H2,(H2,23,25)

InChIKey

SLJXUJZUTPFXRJ-UHFFFAOYSA-N

SMILES

NC(=O)C(CCN1CCCCCC1)(C1=CC=CC=C1)C1=CC=CC=C1

Roles Classification
Chemical Role(s):	Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound )

Biological Role(s):	cholinergic antagonist Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.

Application(s):	mydriatic agent Agent that dilates the pupil. Used in eye diseases and to facilitate eye examination. It may be either a sympathomimetic or parasympatholytic. The latter cause cycloplegia or paralysis of accommodation at high doses and may precipitate glaucoma. cholinergic antagonist Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.

ChEBI Ontology
Outgoing	buzepide (CHEBI:157619) has role cholinergic antagonist (CHEBI:48873) buzepide (CHEBI:157619) has role mydriatic agent (CHEBI:50513) buzepide (CHEBI:157619) is a azepanes (CHEBI:46986) buzepide (CHEBI:157619) is a benzenes (CHEBI:22712) buzepide (CHEBI:157619) is a primary carboxamide (CHEBI:140324) buzepide (CHEBI:157619) is a tertiary amino compound (CHEBI:50996) buzepide (CHEBI:157619) is conjugate base of buzepide(1+) (CHEBI:157622)

Incoming	buzepide(1+) (CHEBI:157622) is conjugate acid of buzepide (CHEBI:157619)

IUPAC Name

4-(azepan-1-yl)-2,2-diphenylbutanamide

Synonyms	Sources
4-(hexahydro-1H-azepinyl)-2,2-diphenylbutanamide	ChEBI
Acemydrite	ChEBI
buzepidonum	ChemIDplus
Calmacid	ChEBI
hexahydro-α,α-diphenyl-1H-azepine-1-butanamide	ChEBI
hexahydro-α,α-diphenyl-1H-azepine-1-butyramide	ChEBI
hexamethamide	ChEBI
mydriamide	ChEBI

Registry Number	Type	Source
3691-21-2	CAS Registry Number	ChemIDplus

Last Modified

09 October 2020