CHEBI:73294 - NPC-567

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ChEBI Name NPC-567 ChEBI ID CHEBI:73294 Definition A ten-membered oligopeptide comprising D-arginyl, L-arginyl, L-prolyl, (4R)-4-hydroxy-L-prolyl, glycyl, L-phenylalanyl, L-seryl, D-phenylalanyl, L-phenylalanyl and L-arginine residues joined in sequence. Stars This entity has been manually annotated by the ChEBI Team. Submitter Margaret Duesbury Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Formula C60H87N19O13 Net Charge 0 Average Mass 1282.45230 Monoisotopic Mass 1281.67307 InChI InChI=1S/C60H87N19O13/c61-39(20-10-24-68-58(62)63)49(83)73-40(21-11-25-69-59(64)65)55(89)78-27-13-23-46(78)56(90)79-33-38(81)31-47(79)54(88)71-32-48(82)72-42(28-35-14-4-1-5-15-35)50(84)77-45(34-80)53(87)76-44(30-37-18-8-3-9-19-37)52(86)75-43(29-36-16-6-2-7-17-36)51(85)74-41(57(91)92)22-12-26-70-60(66)67/h1-9,14-19,38-47,80-81H,10-13,20-34,61H2,(H,71,88)(H,72,82)(H,73,83)(H,74,85)(H,75,86)(H,76,87)(H,77,84)(H,91,92)(H4,62,63,68)(H4,64,65,69)(H4,66,67,70)/t38-,39-,40+,41+,42+,43+,44-,45+,46+,47+/m1/s1 InChIKey RBIXVHPHNGXTCI-QJTYZATASA-N SMILES N[C@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O Roles Classification Chemical Role(s): Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound ) Biological Role(s): bradykinin receptor antagonist An antagonist at the bradykinin receptor. View more via ChEBI Ontology ChEBI Ontology Outgoing NPC-567 (CHEBI:73294) has functional parent bradykinin (CHEBI:3165) NPC-567 (CHEBI:73294) has role bradykinin receptor antagonist (CHEBI:68557) NPC-567 (CHEBI:73294) is a oligopeptide (CHEBI:25676) IUPAC Name D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-L-phenylalanyl-L-seryl-D-phenylalanyl-L-phenylalanyl-L-arginine Synonyms Sources [D-Arg0,Hyp3,D-Phe7]bradykinin ChEBI arg(0)-hyp(3)-phe(7)-bradykinin ChemIDplus Arg-3-hyp-7-phe-bradykinin ChemIDplus D-Arg-Arg-Pro-Hyp-Gly-Phe-Ser-D-Phe-Phe-Arg ChEBI Npc 567 ChemIDplus Registry Numbers Types Sources 109333-26-8 CAS Registry Number ChemIDplus 5422398 Reaxys Registry Number Reaxys Citations Types Sources 11603850 PubMed citation Europe PMC 1462878 PubMed citation Europe PMC 1647192 PubMed citation Europe PMC 1965113 PubMed citation Europe PMC 2008991 PubMed citation Europe PMC 2135209 PubMed citation Europe PMC 2234103 PubMed citation Europe PMC 23597562 PubMed citation Europe PMC 2706751 PubMed citation Europe PMC Last Modified 29 April 2013