guanazole (CHEBI:75425)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	guanazole

ChEBI ID	CHEBI:75425

Definition	An aromatic amine that is 1,2,4-triazole substituted at positions 3 and 5 by amino groups.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C2H5N5

Net Charge

Average Mass

99.09460

Monoisotopic Mass

99.05450

InChI

InChI=1S/C2H5N5/c3-1-5-2(4)7-6-1/h(H5,3,4,5,6,7)

InChIKey

PKWIYNIDEDLDCJ-UHFFFAOYSA-N

SMILES

Nc1n[nH]c(N)n1

Roles Classification
Chemical Role(s):	Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound )

Biological Role(s):	EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that inhibits the action of ribonucleoside-diphosphate reductase (EC 1.17.4.1). DNA synthesis inhibitor Any substance that inhibits the synthesis of DNA.

Application(s):	antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology
Outgoing	guanazole (CHEBI:75425) has role antineoplastic agent (CHEBI:35610) guanazole (CHEBI:75425) has role DNA synthesis inhibitor (CHEBI:59517) guanazole (CHEBI:75425) has role EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor (CHEBI:74213) guanazole (CHEBI:75425) is a aromatic amine (CHEBI:33860) guanazole (CHEBI:75425) is a triazoles (CHEBI:35727)

IUPAC Name

1H-1,2,4-triazole-3,5-diamine

Last Modified

02 September 2013