N-methylquipazine (CHEBI:64164)

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ChEBI Name	N-methylquipazine

ChEBI ID	CHEBI:64164

ChEBI ASCII Name	N-methylquipazine

Definition	An aminoquinoline that consists of quinoline in which the hydrogen at position 2 is substituted by a 4-methylpiperazin-1-yl group. A 5-HT₃ agonist. Has almost the same affinity for 5-HT₃ sites as quipazine but unlike the latter, does not bind to 5-HT_1B sites.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C14H17N3

Net Charge

Average Mass

227.30490

Monoisotopic Mass

227.14225

InChI

InChI=1S/C14H17N3/c1-16-8-10-17(11-9-16)14-7-6-12-4-2-3-5-13(12)15-14/h2-7H,8-11H2,1H3

InChIKey

HOMWNUXPSJQSSU-UHFFFAOYSA-N

SMILES

CN1CCN(CC1)c1ccc2ccccc2n1

Roles Classification
Chemical Role(s):	Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound )

Biological Role(s):	serotonergic agonist An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.

Application(s):	serotonergic agonist An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.

ChEBI Ontology
Outgoing	N-methylquipazine (CHEBI:64164) has role serotonergic agonist (CHEBI:35941) N-methylquipazine (CHEBI:64164) is a N-alkylpiperazine (CHEBI:46845) N-methylquipazine (CHEBI:64164) is a N-arylpiperazine (CHEBI:46848) N-methylquipazine (CHEBI:64164) is a aminoquinoline (CHEBI:36709)

Incoming	N-methylquipazine dimaleate (CHEBI:64162) has part N-methylquipazine (CHEBI:64164)

Registry Number	Type	Source
887071	Reaxys Registry Number	Reaxys

Last Modified

06 July 2016