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InChI=1S/CH4O/c1-2/h2H,1H3
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> Main
CHEBI:5169 - fraxetin
Main
ChEBI Ontology
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ChEBI Name
fraxetin
ChEBI ID
CHEBI:5169
Definition
A hydroxycoumarin that is 6-methoxycoumarin in which the hydrogens at positions 7 and 8 have been replaced by hydroxy groups.
Stars
This entity has been manually annotated by the ChEBI Team.
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Wikipedia
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Read full article at Wikipedia
Formula
C10H8O5
Net Charge
0
Average Mass
208.168
Monoisotopic Mass
208.03717
InChI
InChI=1S/C10H8O5/c1-14-6-4-5-2-3-7(11)15-10(5)9(13)8(6)12/h2-4,12-13H,1H3
InChIKey
HAVWRBANWNTOJX-UHFFFAOYSA-N
SMILES
C12=C(C=C(OC)C(=C1O)O)C=CC(O2)=O
Metabolite of Species
Details
Fraxinus chinensis
subsp.
rhynchophylla
(NCBI:txid126596)
See:
PubMed
Roles Classification
Chemical Role
(s):
antioxidant
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
Biological Role
(s):
Arabidopsis thaliana metabolite
Any plant metabolite that is produced by
Arabidopsis thaliana
.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
apoptosis inhibitor
Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms.
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
antibacterial agent
A substance (or active part thereof) that kills or slows the growth of bacteria.
Application
(s):
anti-inflammatory agent
Any compound that has anti-inflammatory effects.
hepatoprotective agent
Any compound that is able to prevent damage to the liver.
hypoglycemic agent
A drug which lowers the blood glucose level.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
fraxetin (
CHEBI:5169
)
has role
Arabidopsis thaliana
metabolite (
CHEBI:140602
)
fraxetin (
CHEBI:5169
)
has role
anti-inflammatory agent (
CHEBI:67079
)
fraxetin (
CHEBI:5169
)
has role
antibacterial agent (
CHEBI:33282
)
fraxetin (
CHEBI:5169
)
has role
antimicrobial agent (
CHEBI:33281
)
fraxetin (
CHEBI:5169
)
has role
antioxidant (
CHEBI:22586
)
fraxetin (
CHEBI:5169
)
has role
apoptosis inducer (
CHEBI:68495
)
fraxetin (
CHEBI:5169
)
has role
apoptosis inhibitor (
CHEBI:68494
)
fraxetin (
CHEBI:5169
)
has role
hepatoprotective agent (
CHEBI:62868
)
fraxetin (
CHEBI:5169
)
has role
hypoglycemic agent (
CHEBI:35526
)
fraxetin (
CHEBI:5169
)
is a
aromatic ether (
CHEBI:35618
)
fraxetin (
CHEBI:5169
)
is a
hydroxycoumarin (
CHEBI:37912
)
Incoming
fraxin (
CHEBI:5170
)
has functional parent
fraxetin (
CHEBI:5169
)
sideretin (reduced form) (
CHEBI:142095
)
has functional parent
fraxetin (
CHEBI:5169
)
IUPAC Name
7,8-dihydroxy-6-methoxy-2
H
-chromen-2-one
Synonyms
Sources
7,8-dihydroxy-6-methoxy-2-benzopyrone
ChemIDplus
7,8-dihydroxy-6-methoxycoumarin
ChemIDplus
fraxetin
UniProt
Manual Xrefs
Databases
C00002473
KNApSAcK
C09265
KEGG COMPOUND
Fraxetin
Wikipedia
LSM-3712
LINCS
View more database links
Registry Numbers
Types
Sources
198796
Reaxys Registry Number
Reaxys
574-84-5
CAS Registry Number
ChemIDplus
574-84-5
CAS Registry Number
NIST Chemistry WebBook
Citations
Types
Sources
11456117
PubMed citation
Europe PMC
12860476
PubMed citation
Europe PMC
15120578
PubMed citation
Europe PMC
15904944
PubMed citation
Europe PMC
15996779
PubMed citation
Europe PMC
16394523
PubMed citation
Europe PMC
19721227
PubMed citation
Europe PMC
23788190
PubMed citation
Europe PMC
23806420
PubMed citation
Europe PMC
23994349
PubMed citation
Europe PMC
24025985
PubMed citation
Europe PMC
25189268
PubMed citation
Europe PMC
25445053
PubMed citation
Europe PMC
26945887
PubMed citation
Europe PMC
27722139
PubMed citation
Europe PMC
28976788
PubMed citation
Europe PMC
29157824
PubMed citation
Europe PMC
29344176
PubMed citation
Europe PMC
29414667
PubMed citation
Europe PMC
29559590
PubMed citation
Europe PMC
29581584
PubMed citation
Europe PMC
29786751
PubMed citation
Europe PMC
30205426
PubMed citation
Europe PMC
9120770
PubMed citation
Europe PMC
Last Modified
06 October 2020