CHEBI:91749 - tianeptine

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ChEBI Name tianeptine
ChEBI ID CHEBI:91749
Definition A racemate comprising of equimolar amounts of (R)- and (S)-tianeptine. It is an atypical antidepressant used in Europe to treat patients who respond poorly to selective serotonin reuptake inhibitors (SSRIs).
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C21H25ClN2O4S
Net Charge 0
Average Mass 436.950
Monoisotopic Mass 436.12236
Roles Classification
Biological Role(s): mu-opioid receptor agonist
A compound that exhibits agonist activity at the mu-opioid receptor.
Application(s): mu-opioid receptor agonist
A compound that exhibits agonist activity at the mu-opioid receptor.
second generation antipsychotic
Antipsychotic drugs which can have different modes of action but which tend to be less likely than first generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements.
anxiolytic drug
Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
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ChEBI Ontology
Outgoing tianeptine (CHEBI:91749) has part (R)-tianeptine (CHEBI:190007)
tianeptine (CHEBI:91749) has part (S)-tianeptine (CHEBI:190006)
tianeptine (CHEBI:91749) has role μ-opioid receptor agonist (CHEBI:55322)
tianeptine (CHEBI:91749) has role anxiolytic drug (CHEBI:35474)
tianeptine (CHEBI:91749) has role second generation antipsychotic (CHEBI:65191)
tianeptine (CHEBI:91749) is a racemate (CHEBI:60911)
IUPAC Name
rac-7-[(3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid
INNs Sources
tianeptina WHO MedNet
tianeptine WHO MedNet
tianeptine WHO MedNet
tianeptinum WHO MedNet
Synonyms Sources
(±)-7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid S,S-dioxide ChEBI
(±)-tianeptine ChEBI
7-{[(11RS)-3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl]amino}heptanoic acid IUPAC
rac-tianeptine ChEBI
racemic tianeptine ChEBI
Manual Xrefs Databases
2650 DrugCentral
62102 ChemSpider
D02575 KEGG DRUG
HMDB0042038 HMDB
LSM-1626 LINCS
Tianeptine Wikipedia
View more database links
Registry Number Type Source
72797-41-2 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
28 February 2022