CHEBI:34130 - 11,12-EET

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name 11,12-EET
ChEBI ID CHEBI:34130
Definition An EET obtained by formal epoxidation of the 11,12-double bond of arachidonic acid.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Mark Williams
Secondary ChEBI IDs CHEBI:63967
Supplier Information
Download Molfile XML SDF
Formula C20H32O3
Net Charge 0
Average Mass 320.46630
Monoisotopic Mass 320.23514
InChI InChI=1S/C20H32O3/c1-2-3-4-5-9-12-15-18-19(23-18)16-13-10-7-6-8-11-14-17-20(21)22/h6,8-10,12-13,18-19H,2-5,7,11,14-17H2,1H3,(H,21,22)/b8-6-,12-9-,13-10-
InChIKey DXOYQVHGIODESM-KROJNAHFSA-N
SMILES CCCCC\C=C/CC1OC1C\C=C/C\C=C/CCCC(O)=O
Metabolite of Species Details
Mus musculus (NCBI:txid10090) Source: BioModels - MODEL1507180067 See: PubMed
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
xenobiotic metabolite
Any metabolite produced by metabolism of a xenobiotic compound.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via EET )
Application(s): platelet aggregation inhibitor
A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
(via EET )
anti-inflammatory drug
A substance that reduces or suppresses inflammation.
(via EET )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 11,12-EET (CHEBI:34130) has role mouse metabolite (CHEBI:75771)
11,12-EET (CHEBI:34130) has role xenobiotic metabolite (CHEBI:76206)
11,12-EET (CHEBI:34130) is a EET (CHEBI:64007)
11,12-EET (CHEBI:34130) is conjugate acid of 11,12-EET(1−) (CHEBI:76625)
Incoming 11,12-epoxy-(5Z,8Z,14Z)-icosatrienoyl-CoA (CHEBI:137047) has functional parent 11,12-EET (CHEBI:34130)
2-glyceryl 11,12-epoxy-(5Z,8Z,14Z)-icosatrienoate (CHEBI:132119) has functional parent 11,12-EET (CHEBI:34130)
N-[(5Z,8Z,14Z)-11,12-epoxyicosatrienoyl]ethanolamine (CHEBI:136990) has functional parent 11,12-EET (CHEBI:34130)
(11R,12S)-EET (CHEBI:132277) is a 11,12-EET (CHEBI:34130)
(11S,12R)-EET (CHEBI:132276) is a 11,12-EET (CHEBI:34130)
11,12-EET(1−) (CHEBI:76625) is conjugate base of 11,12-EET (CHEBI:34130)
IUPAC Name
(5Z,8Z)-10-{3-[(2Z)-oct-2-en-1-yl]oxiran-2-yl}deca-5,8-dienoic acid
Synonyms Sources
(+/-)11,12-EpETrE LIPID MAPS
(5Z,8Z,14Z)-11,12-Epoxyeicosa-5,8,14-trienoic acid KEGG COMPOUND
(5Z,8Z,14Z)-11,12-Epoxyicosa-5,8,14-trienoic acid KEGG COMPOUND
11,12-EET KEGG COMPOUND
11,12-EpETrE SUBMITTER
11,12-epoxy-5Z,8Z,11Z-icosatrienoic acid ChEBI
11,12-epoxy-5Z,8Z,14Z-eicosatrienoic acid LIPID MAPS
11,12-epoxyarachidonic acid ChEBI
all-cis-11,12-epoxyeicosa-5,8,11-trienoic acid ChEBI
Manual Xrefs Databases
C14770 KEGG COMPOUND
HMDB0010409 HMDB
LMFA03080004 LIPID MAPS
View more database links
Registry Numbers Types Sources
123931-40-8 CAS Registry Number SUBMITTER
5067342 Reaxys Registry Number Reaxys
Last Modified
28 July 2017