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lixisenatide |
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CHEBI:85662 |
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A forty-four membered polypeptide consisting of L-His, Gly, L-Glu, Gly, L-Thr, L-Phe, L-Thr, L-Ser, L-Asp, L-Leu, L-Ser, L-Lys, L-Gln, L-Met, L-Glu, L-Glu, L-Glu, L-Ala, L-Val, L-Arg, L-Leu, L-Phe, L-Ile, L-Glu, L-Trp, L-Leu, L-Lys, L-Asn, Gly, Gly, LPro, L-Ser, L-Ser, Gly, L-Ala, L-Pro, L-Pro, L-Ser, L-Lys, L-Lys, L-Lys, L-Lys, L-Lys, and L-Lys-NH2 residues joined in sequence. Used as an adjunct to diet and exercise for the treatment of adults with type II diabetes. |
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![](images/goldenstar.gif) ![](images/goldenstar.gif)
This entity has been manually annotated by the ChEBI Team.
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Molfile
XML
SDF
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InChI=1S/C215H347N61O65S/c1- 16- 115(10) 173(210(337) 256- 141(68- 74- 170(299) 300) 194(321) 261- 148(94- 122- 98- 232- 126- 50- 24- 23- 49- 124(122) 126) 199(326) 258- 143(89- 111(2) 3) 196(323) 247- 134(58- 32- 40- 83- 223) 189(316) 262- 149(96- 160(226) 285) 180(307) 235- 100- 161(286) 233- 104- 165(290) 274- 85- 42- 60- 156(274) 207(334) 267- 154(108- 280) 206(333) 265- 151(105- 277) 181(308) 237- 101- 162(287) 239- 117(12) 213(340) 276- 87- 44- 62- 158(276) 214(341) 275- 86- 43- 61- 157(275) 208(335) 268- 153(107- 279) 204(331) 249- 132(56- 30- 38- 81- 221) 187(314) 246- 131(55- 29- 37- 80- 220) 186(313) 245- 130(54- 28- 36- 79- 219) 185(312) 244- 129(53- 27- 35- 78- 218) 184(311) 243- 128(52- 26- 34- 77- 217) 183(310) 242- 127(176(227) 303) 51- 25- 33- 76- 216) 272- 201(328) 146(92- 120- 45- 19- 17- 20- 46- 120) 260- 197(324) 144(90- 112(4) 5) 257- 190(317) 135(59- 41- 84- 231- 215(228) 229) 255- 209(336) 172(114(8) 9) 271- 177(304) 116(11) 240- 182(309) 138(65- 71- 167(293) 294) 251- 192(319) 139(66- 72- 168(295) 296) 252- 193(320) 140(67- 73- 169(297) 298) 253- 195(322) 142(75- 88- 342- 15) 254- 191(318) 137(63- 69- 159(225) 284) 250- 188(315) 133(57- 31- 39- 82- 222) 248- 203(330) 152(106- 278) 266- 198(325) 145(91- 113(6) 7) 259- 200(327) 150(97- 171(301) 302) 263- 205(332) 155(109- 281) 269- 212(339) 175(119(14) 283) 273- 202(329) 147(93- 121- 47- 21- 18- 22- 48- 121) 264- 211(338) 174(118(13) 282) 270- 164(289) 103- 236- 179(306) 136(64- 70- 166(291) 292) 241- 163(288) 102- 234- 178(305) 125(224) 95- 123- 99- 230- 110- 238- 123/h17- 24,45- 50,98- 99,110- 119,125,127- 158,172- 175,232,277- 283H,16,25- 44,51- 97,100- 109,216- 224H2,1- 15H3,(H2,225,284) (H2,226,285) (H2,227,303) (H,230,238) (H,233,286) (H,234,305) (H,235,307) (H,236,306) (H,237,308) (H,239,287) (H,240,309) (H,241,288) (H,242,310) (H,243,311) (H,244,312) (H,245,313) (H,246,314) (H,247,323) (H,248,330) (H,249,331) (H,250,315) (H,251,319) (H,252,320) (H,253,322) (H,254,318) (H,255,336) (H,256,337) (H,257,317) (H,258,326) (H,259,327) (H,260,324) (H,261,321) (H,262,316) (H,263,332) (H,264,338) (H,265,333) (H,266,325) (H,267,334) (H,268,335) (H,269,339) (H,270,289) (H,271,304) (H,272,328) (H,273,329) (H,291,292) (H,293,294) (H,295,296) (H,297,298) (H,299,300) (H,301,302) (H4,228,229,231) /t115- ,116- ,117- ,118+,119+,125- ,127- ,128- ,129- ,130- ,131- ,132- ,133- ,134- ,135- ,136- ,137- ,138- ,139- ,140- ,141- ,142- ,143- ,144- ,145- ,146- ,147- ,148- ,149- ,150- ,151- ,152- ,153- ,154- ,155- ,156- ,157- ,158- ,172- ,173- ,174- ,175- /m0/s1 |
XVVOERDUTLJJHN-IAEQDCLQSA-N |
CC[C@H] (C) [C@H] (NC(=O) [C@H] (Cc1ccccc1) NC(=O) [C@H] (CC(C) C) NC(=O) [C@H] (CCCNC(N) =N) NC(=O) [C@@H] (NC(=O) [C@H] (C) NC(=O) [C@H] (CCC(O) =O) NC(=O) [C@H] (CCC(O) =O) NC(=O) [C@H] (CCC(O) =O) NC(=O) [C@H] (CCSC) NC(=O) [C@H] (CCC(N) =O) NC(=O) [C@H] (CCCCN) NC(=O) [C@H] (CO) NC(=O) [C@H] (CC(C) C) NC(=O) [C@H] (CC(O) =O) NC(=O) [C@H] (CO) NC(=O) [C@@H] (NC(=O) [C@H] (Cc1ccccc1) NC(=O) [C@@H] (NC(=O) CNC(=O) [C@H] (CCC(O) =O) NC(=O) CNC(=O) [C@@H] (N) Cc1c[nH] cn1) [C@@H] (C) O) [C@@H] (C) O) C(C) C) C(=O) N[C@@H] (CCC(O) =O) C(=O) N[C@@H] (Cc1c[nH] c2ccccc12) C(=O) N[C@@H] (CC(C) C) C(=O) N[C@@H] (CCCCN) C(=O) N[C@@H] (CC(N) =O) C(=O) NCC(=O) NCC(=O) N1CCC[C@H] 1C(=O) N[C@@H] (CO) C(=O) N[C@@H] (CO) C(=O) NCC(=O) N[C@@H] (C) C(=O) N1CCC[C@H] 1C(=O) N1CCC[C@H] 1C(=O) N[C@@H] (CO) C(=O) N[C@@H] (CCCCN) C(=O) N[C@@H] (CCCCN) C(=O) N[C@@H] (CCCCN) C(=O) N[C@@H] (CCCCN) C(=O) N[C@@H] (CCCCN) C(=O) N[C@@H] (CCCCN) C(N) =O |
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Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
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glucagon-like peptide-1 receptor agonist
An agonist that binds to and activates glucagon-like peptide-1 (GLP-1) receptors.
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neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
hypoglycemic agent
A drug which lowers the blood glucose level.
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View more via ChEBI Ontology
L- histidylglycyl- L- α- glutamylglycyl- L- threonyl- L- phenylalanyl- L- threonyl- L- seryl- L- α- aspartyl- L- leucyl- L- seryl- L- lysyl- L- glutaminyl- L- methionyl- L- α- glutamyl- L- α- glutamyl- L- α- glutamyl- L- alanyl- L- valyl- L- arginyl- L- leucyl- L- phenylalanyl- L- isoleucyl- L- α- glutamyl- L- tryptophyl- L- leucyl- L- lysyl- L- asparaginylglycylglycyl- L- prolyl- L- seryl- L- serylglycyl- L- alanyl- L- prolyl- L- prolyl- L- seryl- L- lysyl- L- lysyl- L- lysyl- L- lysyl- L- lysyl- L- lysinamide
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lixisenatida
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WHO MedNet
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lixisenatide
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WHO MedNet
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lixisénatide
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WHO MedNet
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lixisenatidum
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WHO MedNet
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AQVE-10010
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ChemIDplus
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AVE 0010
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ChemIDplus
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AVE0010
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ChemIDplus
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des- 38- proline- exendine- 4 (Heloderma suspectum)- (1- 39)- peptidylpenta- L- lysyl- L- lysinamide
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ChemIDplus
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DesPro38Exendin-4(1-39)-Lys6-NH2
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ChemIDplus
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H-HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPSKKKKKK-NH2
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ChEBI
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H-HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPSKKKKKK-NH2
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ChEBI
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H- His- Gly- Glu- Gly- Thr- Phe- Thr- Ser- Asp- Leu- Ser- Lys- Gln- Met- Glu- Glu- Glu- Ala- Val- Arg- Leu- Phe- Ile- Glu- Trp- Leu- Lys- Asn- Gly- Gly- Pro- Ser- Ser- Gly- Ala- Pro- Pro- Ser- Lys- Lys- Lys- Lys- Lys- Lys- NH2
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ChEBI
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H- L- His- Gly- L- Glu- Gly- L- Thr- L- Phe- L- Thr- L- Ser- L- Asp- L- Leu- L- Ser- L- Lys- L- Gln- L- Met- L- Glu- L- Glu- L- Glu- L- Ala- L- Val- L- Arg- L- Leu- L- Phe- L- Ile- L- Glu- L- Trp- L- Leu- L- Lys- L- Asn- Gly- Gly- L- Pro- L- Ser- L- Ser- Gly- L- Ala- L- Pro- L- Pro- L- Ser- L- Lys- L- Lys- L- Lys- L- Lys- L- Lys- L- Lys- NH2
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ChEBI
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ZP 10
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ChemIDplus
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ZP10A peptide
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ChemIDplus
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Adlyxin
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ChEBI
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Lyxumia
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ChemIDplus
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23952540
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Reaxys Registry Number
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Reaxys
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320367-13-3
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CAS Registry Number
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ChemIDplus
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19629885
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PubMed citation
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Europe PMC
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21391833
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23537041
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