CHEBI:67175 - cortistatin D

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ChEBI Name cortistatin D
ChEBI ID CHEBI:67175
Definition A member of the class of cortistatins that is cortistatin C in which the hydrogen at position 17 has been replaced by a hydroxy group.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C30H34N2O5
Net Charge 0
Average Mass 502.60140
Monoisotopic Mass 502.24677
InChI InChI=1S/C30H34N2O5/c1-27-8-6-19-13-21-25(34)26(35)22(32(2)3)15-28(21)9-10-29(19,37-28)23(27)14-24(33)30(27,36)20-5-4-17-7-11-31-16-18(17)12-20/h4-7,11-13,16,22-23,25-26,34-36H,8-10,14-15H2,1-3H3/t22-,23+,25+,26+,27-,28+,29+,30+/m0/s1
InChIKey VSVYWUPPYDXESC-OMXDIREYSA-N
SMILES [H][C@@]12CC(=O)[C@](O)(c3ccc4ccncc4c3)[C@@]1(C)CC=C1C=C3[C@@H](O)[C@H](O)[C@H](C[C@]33CC[C@]21O3)N(C)C
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
Application(s): angiogenesis modulating agent
An agent that modulates the physiologic angiogenesis process. This is accomplished by endogenous angiogenic proteins and a variety of other chemicals and pharmaceutical agents.
(via cortistatins )
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ChEBI Ontology
Outgoing cortistatin D (CHEBI:67175) has functional parent cortistatin C (CHEBI:67174)
cortistatin D (CHEBI:67175) is a cortistatins (CHEBI:67169)
cortistatin D (CHEBI:67175) is a cyclic ketone (CHEBI:3992)
cortistatin D (CHEBI:67175) is a diol (CHEBI:23824)
cortistatin D (CHEBI:67175) is a secondary alcohol (CHEBI:35681)
cortistatin D (CHEBI:67175) is a tertiary α-hydroxy ketone (CHEBI:139592)
cortistatin D (CHEBI:67175) is a tertiary alcohol (CHEBI:26878)
IUPAC Name
(1R,2R,3S,5R)-3-(dimethylamino)-1,2,17α-trihydroxy-17β-(isoquinolin-7-yl)-5,8α-epoxy-9,19-cyclo-9,10-secoandrosta-9(11),10-dien-16-one
Synonyms Sources
(−)-cortistatin D ChEBI
(1R,2R,3S,5R,8α,17α)-3-(dimethylamino)-1,2,17-trihydroxy-17-(isoquinolin-7-yl)-5,8-epoxy-9,19-cyclo-9,10-secoandrosta-9(11),10-dien-16-one IUPAC
Registry Number Type Source
10504489 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
16522087 PubMed citation Europe PMC
17765550 PubMed citation Europe PMC
Last Modified
07 February 2018