CHEBI:65673 - cratoxyarborenone C

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ChEBI Name cratoxyarborenone C
ChEBI ID CHEBI:65673
Definition A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1 and 3, methoxy groups at positions 5 and 7 and two isoprenyl groups at positions 2 and 8 respectively. It is isolated from Cratoxylum Sumatranum and exhibits cytotoxicity towards the KB (human oral epidermoid) cancer cell line
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C25H28O6
Net Charge 0
Average Mass 424.48620
Monoisotopic Mass 424.18859
InChI InChI=1S/C25H28O6/c1-13(2)7-9-15-17(26)11-19-22(23(15)27)24(28)21-16(10-8-14(3)4)18(29-5)12-20(30-6)25(21)31-19/h7-8,11-12,26-27H,9-10H2,1-6H3
InChIKey PGWGLEHDWSDHBH-UHFFFAOYSA-N
SMILES COc1cc(OC)c2oc3cc(O)c(CC=C(C)C)c(O)c3c(=O)c2c1CC=C(C)C
Metabolite of Species Details
Cratoxylum Sumatranum (IPNI:433074-1) Found in stem (BTO:0001300). Previous component: stem bark; See: PubMed
Cratoxylum Sumatranum (IPNI:433074-1) Found in twig (BTO:0001411). See: PubMed
Cratoxylum Sumatranum (IPNI:433074-1) Found in leaf (BTO:0000713). See: PubMed
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing cratoxyarborenone C (CHEBI:65673) has role antineoplastic agent (CHEBI:35610)
cratoxyarborenone C (CHEBI:65673) has role metabolite (CHEBI:25212)
cratoxyarborenone C (CHEBI:65673) is a aromatic ether (CHEBI:35618)
cratoxyarborenone C (CHEBI:65673) is a polyphenol (CHEBI:26195)
cratoxyarborenone C (CHEBI:65673) is a xanthones (CHEBI:51149)
IUPAC Name
1,3-dihydroxy-5,7-dimethoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one
Synonym Source
1,3-dihydroxy-5,7-dimethoxy-2,8-diisoprenylxanthone ChEBI
Registry Number Type Source
9093044 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
11908969 PubMed citation Europe PMC
Last Modified
18 December 2012