piromidic acid (CHEBI:32019)

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ChEBI Name	piromidic acid

ChEBI ID	CHEBI:32019

Definition	A pyridopyrimidine that is 5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid, substituted at position 2 by a pyrrolidin-1-yl group and at position 8 by an ethyl group. A synthetic antibacterial which is used for the treatment of urinary tract and intestinal infections.

Stars	This entity has been manually annotated by the ChEBI Team.

Secondary ChEBI IDs	CHEBI:94597

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Formula

C14H16N4O3

Net Charge

Average Mass

288.302

Monoisotopic Mass

288.12224

InChI

InChI=1S/C14H16N4O3/c1-2-17-8-10(13(20)21)11(19)9-7-15-14(16-12(9)17)18-5-3-4-6-18/h7-8H,2-6H2,1H3,(H,20,21)

InChIKey

RCIMBBZXSXFZBV-UHFFFAOYSA-N

SMILES

CCN1C=C(C(=O)C2=CN=C(N=C21)N3CCCC3)C(O)=O

Roles Classification
Chemical Role(s):	Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound ) Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Bronsted base). (via oxoacid )

Biological Role(s):	antibacterial drug A drug used to treat or prevent bacterial infections. DNA synthesis inhibitor Any substance that inhibits the synthesis of DNA. antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. (via quinolone antibiotic ) (via heterocyclic antibiotic )

Application(s):	antibacterial drug A drug used to treat or prevent bacterial infections.

ChEBI Ontology
Outgoing	piromidic acid (CHEBI:32019) has role antibacterial drug (CHEBI:36047) piromidic acid (CHEBI:32019) has role DNA synthesis inhibitor (CHEBI:59517) piromidic acid (CHEBI:32019) is a monocarboxylic acid (CHEBI:25384) piromidic acid (CHEBI:32019) is a pyridopyrimidine (CHEBI:38932) piromidic acid (CHEBI:32019) is a pyrrolidines (CHEBI:38260) piromidic acid (CHEBI:32019) is a quinolone antibiotic (CHEBI:86324) piromidic acid (CHEBI:32019) is a tertiary amino compound (CHEBI:50996)

IUPAC Name

8-ethyl-5-oxo-2-(pyrrolidin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid

Synonyms	Sources
8-ethyl-5,8-dihydro-5-oxo-2-(1-pyrrolidinyl)pyrido(2,3-d)pyrimidine-6-carboxylic acid	ChemIDplus
pyromidic acid	DrugCentral

Last Modified

26 October 2018