CHEBI:67988 - ginsenoside Rd

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name ginsenoside Rd
ChEBI ID CHEBI:67988
Definition A ginsenoside found in Panax ginseng and Panax japonicus var. major that is (20S)-ginsenoside Rg3 in which the hydroxy group at position 20 has been converted to its β-D-glucopyranoside.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C48H82O18
Net Charge 0
Average Mass 947.15390
Monoisotopic Mass 946.55012
InChI InChI=1S/C48H82O18/c1-22(2)10-9-14-48(8,66-42-39(60)36(57)33(54)26(20-50)62-42)23-11-16-47(7)31(23)24(52)18-29-45(5)15-13-30(44(3,4)28(45)12-17-46(29,47)6)64-43-40(37(58)34(55)27(21-51)63-43)65-41-38(59)35(56)32(53)25(19-49)61-41/h10,23-43,49-60H,9,11-21H2,1-8H3/t23-,24+,25+,26+,27+,28-,29+,30-,31-,32+,33+,34+,35-,36-,37-,38+,39+,40+,41-,42-,43-,45-,46+,47+,48-/m0/s1
InChIKey RLDVZILFNVRJTL-IWFVLDDISA-N
SMILES [H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)CC[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C)[C@]3([H])CC[C@@]21C)[C@](C)(CCC=C(C)C)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Metabolite of Species Details
Panax japonicus var. major (NCBI:txid45211) Found in root (BTO:0001188). Ethanolic extract of dried and pulverized roots See: PubMed
Roles Classification
Biological Role(s): apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via saponin )
Application(s): vulnerary
A drug used in treating and healing of wounds.
neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
anti-inflammatory drug
A substance that reduces or suppresses inflammation.
immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing ginsenoside Rd (CHEBI:67988) has functional parent (20S)-ginsenoside Rg3 (CHEBI:67991)
ginsenoside Rd (CHEBI:67988) has role anti-inflammatory drug (CHEBI:35472)
ginsenoside Rd (CHEBI:67988) has role apoptosis inducer (CHEBI:68495)
ginsenoside Rd (CHEBI:67988) has role immunosuppressive agent (CHEBI:35705)
ginsenoside Rd (CHEBI:67988) has role neuroprotective agent (CHEBI:63726)
ginsenoside Rd (CHEBI:67988) has role plant metabolite (CHEBI:76924)
ginsenoside Rd (CHEBI:67988) has role vulnerary (CHEBI:73336)
ginsenoside Rd (CHEBI:67988) is a β-D-glucoside (CHEBI:22798)
ginsenoside Rd (CHEBI:67988) is a ginsenoside (CHEBI:74978)
ginsenoside Rd (CHEBI:67988) is a tetracyclic triterpenoid (CHEBI:26893)
Incoming ginsenoside Rb1 (CHEBI:67989) has functional parent ginsenoside Rd (CHEBI:67988)
IUPAC Name
(3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
Synonyms Sources
(20S)-ginsenoside Rd UniProt
(3β,12β,20S)-20-[(β-D-glucopyranosyl)oxy]-3-[(β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl)oxy]dammar-24-en-12-ol ChEBI
(GS)-Rd ChEBI
2-O-β-D-glucopyranosyl-(3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammara-24-en-3-yl-β-D-glucopyranoside ChemIDplus
3-O-(β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl)-20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol ChEBI
G-Rd ChEBI
GS-Rd ChEBI
Gypenoside VIII ChemIDplus
Manual Xref Database
CPD-9249 MetaCyc
View more database links
Registry Numbers Types Sources
52705-93-8 CAS Registry Number ChemIDplus
5723313 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
18256474 PubMed citation Europe PMC
21185898 PubMed citation Europe PMC
21219973 PubMed citation Europe PMC
21417387 PubMed citation Europe PMC
21664366 PubMed citation Europe PMC
21811848 PubMed citation Europe PMC
21872268 PubMed citation Europe PMC
21899993 PubMed citation Europe PMC
21945003 PubMed citation Europe PMC
21982435 PubMed citation Europe PMC
22061660 PubMed citation Europe PMC
22076303 PubMed citation Europe PMC
22227208 PubMed citation Europe PMC
22231470 PubMed citation Europe PMC
22233205 PubMed citation Europe PMC
22300288 PubMed citation Europe PMC
22683911 PubMed citation Europe PMC
22864746 PubMed citation Europe PMC
23073826 PubMed citation Europe PMC
23321003 PubMed citation Europe PMC
23399764 PubMed citation Europe PMC
23463404 PubMed citation Europe PMC
23568202 PubMed citation Europe PMC
23717157 PubMed citation Europe PMC
23717173 PubMed citation Europe PMC
23738998 PubMed citation Europe PMC
Last Modified
22 January 2019