N-benzyl-4-sulfamoylbenzamide (CHEBI:41231)

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ChEBI Name	N-benzyl-4-sulfamoylbenzamide

ChEBI ID	CHEBI:41231

ChEBI ASCII Name	N-benzyl-4-sulfamoylbenzamide

Definition	A secondary carboxamide resulting from the formal condensation of the carboxy group of 4-sulfamoylbenzoic acid with the amino group of 1-phenylmethanamine. It is a potent inhibitor of carbonic anhydrase II.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

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Formula

C14H14N2O3S

Net Charge

Average Mass

290.340

Monoisotopic Mass

290.07251

InChI

InChI=1S/C14H14N2O3S/c15-20(18,19)13-8-6-12(7-9-13)14(17)16-10-11-4-2-1-3-5-11/h1-9H,10H2,(H,16,17)(H2,15,18,19)

InChIKey

CZKNSZUJCJHTTM-UHFFFAOYSA-N

SMILES

NS(=O)(=O)C1=CC=C(C=C1)C(=O)NCC1=CC=CC=C1

Metabolite of Species	Details
Colletotrichum sublineola (NCBI:txid1173701)	Species also known as Colletotrichum sublineolum. See: PubMed

Roles Classification
Biological Role(s):	EC 4.2.1.1 (carbonic anhydrase) inhibitor An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of carbonic anhydrase (EC 4.2.1.1). Such compounds reduce the secretion of H+ ions by the proximal kidney tubule. fungal metabolite Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.

ChEBI Ontology
Outgoing	N-benzyl-4-sulfamoylbenzamide (CHEBI:41231) has role EC 4.2.1.1 (carbonic anhydrase) inhibitor (CHEBI:23018) N-benzyl-4-sulfamoylbenzamide (CHEBI:41231) has role fungal metabolite (CHEBI:76946) N-benzyl-4-sulfamoylbenzamide (CHEBI:41231) is a benzamides (CHEBI:22702) N-benzyl-4-sulfamoylbenzamide (CHEBI:41231) is a benzenes (CHEBI:22712) N-benzyl-4-sulfamoylbenzamide (CHEBI:41231) is a secondary carboxamide (CHEBI:140325) N-benzyl-4-sulfamoylbenzamide (CHEBI:41231) is a sulfonamide (CHEBI:35358)

IUPAC Name

N-benzyl-4-sulfamoylbenzamide

Synonyms	Sources
4-(aminosulfonyl)-N-benzylbenzamide	ChEBI
4-(benzylcarbamoyl)benzenesulfonamide	ChEBI
N-benzyl-4-(aminosulfonyl)benzamide	ChEBI
N-benzyl-4-sulfamoyl-benzamide	PDBeChem

Registry Number	Type	Source
107619-27-2	CAS Registry Number	ChEBI

Last Modified

31 May 2022

General Comment
2022-05-31	Relevant articles: https://doi.org/10.1039/C5MD00542F