CHEBI:66404 - moromycin B

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name moromycin B
ChEBI ID CHEBI:66404
Definition An angucycline that consists of tetrangomycin linked to a deoxy sugar moiety at position 9 via a C-glycosidic bond. It is isolated from Streptomyces sp.KY002 and exhibits cytotoxicity against human lung cancer and MCF-7 human breast cancer cells.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C31H30O10
Net Charge 0
Average Mass 562.56390
Monoisotopic Mass 562.18390
InChI InChI=1S/C31H30O10/c1-12-18(32)8-22-30(39-12)41-29-13(2)38-20(9-21(29)40-22)15-6-7-17-25(26(15)34)28(36)16-5-4-14-10-31(3,37)11-19(33)23(14)24(16)27(17)35/h4-7,12-13,20-22,29-30,34,37H,8-11H2,1-3H3/t12-,13+,20+,21+,22-,29+,30-,31+/m0/s1
InChIKey IVVLBSCKLIYBCU-GEMPFEMJSA-N
SMILES [H][C@@]12C[C@@H](O[C@H](C)[C@@]1([H])O[C@]1([H])O[C@@H](C)C(=O)C[C@]1([H])O2)c1ccc2C(=O)c3c(ccc4C[C@@](C)(O)CC(=O)c34)C(=O)c2c1O
Metabolite of Species Details
Streptomyces sp. (NCBI:txid1931) of strain KY002 See: PubMed
Roles Classification
Biological Role(s): antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via angucycline antibiotic )
bacterial metabolite
Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
(via angucycline )
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing moromycin B (CHEBI:66404) has functional parent tetrangomycin (CHEBI:32211)
moromycin B (CHEBI:66404) has role antimicrobial agent (CHEBI:33281)
moromycin B (CHEBI:66404) has role antineoplastic agent (CHEBI:35610)
moromycin B (CHEBI:66404) is a C-glycosyl compound (CHEBI:20857)
moromycin B (CHEBI:66404) is a angucycline antibiotic (CHEBI:70737)
Registry Number Type Source
19172513 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
18666798 PubMed citation Europe PMC
Last Modified
22 October 2012