herbacetin (CHEBI:27673)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	herbacetin

ChEBI ID	CHEBI:27673

Definition	A pentahydroxyflavone that is kaempferol substituted by a hydroxy group at position 8. It is a natural flavonoid from flaxseed which exerts antioxidant, anti-inflammatory and anticancer activities.

Stars	This entity has been manually annotated by the ChEBI Team.

Secondary ChEBI IDs	CHEBI:2322, CHEBI:20809

Supplier Information

Download	Molfile XML SDF

Wikipedia	License

Read full article at Wikipedia

Formula

C15H10O7

Net Charge

Average Mass

302.238

Monoisotopic Mass

302.04265

InChI

InChI=1S/C15H10O7/c16-7-3-1-6(2-4-7)14-13(21)12(20)10-8(17)5-9(18)11(19)15(10)22-14/h1-5,16-19,21H

InChIKey

ZDOTZEDNGNPOEW-UHFFFAOYSA-N

SMILES

OC1=CC=C(C=C1)C1=C(O)C(=O)C2=C(O1)C(O)=C(O)C=C2O

Metabolite of Species	Details
Rhodiola rosea (NCBI:txid203015)	Identified in rhizomes and roots. See: PubMed
Ephedra sinica (NCBI:txid33152)	See: PubMed

Roles Classification
Biological Role(s):	EC 4.1.1.17 (ornithine decarboxylase) inhibitor An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of ornithine decarboxylase (EC 4.1.1.17). apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of SARS coronavirus main proteinase (EC 3.4.22.69).

Application(s):	antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. angiogenesis inhibitor An agent and endogenous substances that antagonize or inhibit the development of new blood vessels. antilipemic drug A substance used to treat hyperlipidemia (an excess of lipids in the blood). anti-inflammatory agent Any compound that has anti-inflammatory effects.

ChEBI Ontology
Outgoing	herbacetin (CHEBI:27673) has functional parent kaempferol (CHEBI:28499) herbacetin (CHEBI:27673) has role angiogenesis inhibitor (CHEBI:48422) herbacetin (CHEBI:27673) has role anti-inflammatory agent (CHEBI:67079) herbacetin (CHEBI:27673) has role antilipemic drug (CHEBI:35679) herbacetin (CHEBI:27673) has role antineoplastic agent (CHEBI:35610) herbacetin (CHEBI:27673) has role apoptosis inducer (CHEBI:68495) herbacetin (CHEBI:27673) has role EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor (CHEBI:147285) herbacetin (CHEBI:27673) has role EC 4.1.1.17 (ornithine decarboxylase) inhibitor (CHEBI:139556) herbacetin (CHEBI:27673) has role plant metabolite (CHEBI:76924) herbacetin (CHEBI:27673) is a 7-hydroxyflavonol (CHEBI:52267) herbacetin (CHEBI:27673) is a pentahydroxyflavone (CHEBI:25883)

IUPAC Name

3,5,7,8-tetrahydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one

Synonyms	Sources
3,4',5,7,8-pentahydroxyflavone	ChEBI
3,5,7,8-tetrahydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one	IUPAC
8-hydroxykaempferol	KEGG COMPOUND
herbacetin	LIPID MAPS

Registry Number	Type	Source
527-95-7	CAS Registry Number	ChEBI

Last Modified

17 August 2020