avibactam sodium (CHEBI:85982)

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ChEBI Name	avibactam sodium

ChEBI ID	CHEBI:85982

Definition	An organic sodium salt that is the monosodium salt of avibactam. Used in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis.

Stars	This entity has been manually annotated by the ChEBI Team.

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Formula

C7H10N3NaO6S

Net Charge

Average Mass

287.22600

Monoisotopic Mass

287.01880

InChI

InChI=1S/C7H11N3O6S.Na/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15;/h4-5H,1-3H2,(H2,8,11)(H,13,14,15);/q;+1/p-1/t4-,5+;/m1./s1

InChIKey

RTCIKUMODPANKX-JBUOLDKXSA-M

SMILES

[Na+].NC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OS([O-])(=O)=O

Roles Classification
Biological Role(s):	EC 3.5.2.6 (beta-lactamase) inhibitor An EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor that interferes with the action of beta-lactamase (EC 3.5.2.6). antibacterial drug A drug used to treat or prevent bacterial infections. antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.

Application(s):	antibacterial drug A drug used to treat or prevent bacterial infections.

ChEBI Ontology
Outgoing	avibactam sodium (CHEBI:85982) has part avibactam(1−) (CHEBI:85988) avibactam sodium (CHEBI:85982) has role antibacterial drug (CHEBI:36047) avibactam sodium (CHEBI:85982) has role antimicrobial agent (CHEBI:33281) avibactam sodium (CHEBI:85982) has role EC 3.5.2.6 (β-lactamase) inhibitor (CHEBI:35625) avibactam sodium (CHEBI:85982) is a organic sodium salt (CHEBI:38700)

Incoming	Avycaz (CHEBI:85989) has part avibactam sodium (CHEBI:85982)

IUPAC Name

sodium ({[(2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl]oxy}sulfonyl)oxidanide

Synonym	Source
NXL 104	ChemIDplus

Last Modified

10 June 2015