CHEBI:9437 - temoporfin

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ChEBI Name temoporfin
ChEBI ID CHEBI:9437
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C44H32N4O4
Net Charge 0
Average Mass 680.74944
Monoisotopic Mass 680.24236
InChI InChI=1S/C44H32N4O4/c49-29-9-1-5-25(21-29)41-33-13-15-35(45-33)42(26-6-2-10-30(50)22-26)37-17-19-39(47-37)44(28-8-4-12-32(52)24-28)40-20-18-38(48-40)43(36-16-14-34(41)46-36)27-7-3-11-31(51)23-27/h1-17,19,21-24,46-47,49-52H,18,20H2/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-
InChIKey LYPFDBRUNKHDGX-LWQDQPMZSA-N
SMILES Oc1cccc(c1)-c1c2CCc(n2)c(-c2cccc(O)c2)c2ccc([nH]2)c(-c2cccc(O)c2)c2ccc(n2)c(-c2cccc(O)c2)c2ccc1[nH]2
Roles Classification
Biological Role(s): cofactor
An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).
(via porphyrins )
Application(s): photosensitizing agent
A chemical compound that can be excited by light of a specific wavelength and subsequently transfer energy to a chosen reactant. This is commonly molecular oxygen within a cancer tissue, which is converted to (highly rective) singlet state oxygen. This rapidly reacts with any nearby biomolecules, ultimately killing the cancer cells.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing temoporfin (CHEBI:9437) has role photosensitizing agent (CHEBI:47868)
temoporfin (CHEBI:9437) is a chlorins (CHEBI:33910)
IUPAC Name
3,3',3'',3'''-(2,3-dihydroporphyrin-5,10,15,20-tetrayl)tetraphenol
Synonyms Sources
2,3-dihydro-5,10,15,20-tetra(m-hydroxyphenyl)porphyrin Patent
3,3',3'',3'''-(7,8-dihydro-21H,23H-porphine-5,10,15,20-tetrayl)tetrakisphenol ChemIDplus
3,3',3'',3'''-(7,8-dihydroporphyrin-5,10,15,20-tetrayl)tetraphenol ChemIDplus
Foscan KEGG COMPOUND
m-THPC Patent
meso-tetrahydroxyphenylchlorin ChemIDplus
Temoporfin KEGG COMPOUND
Manual Xrefs Databases
2588 DrugCentral
C11730 KEGG COMPOUND
D06066 KEGG DRUG
EP337601 Patent
US4992257 Patent
View more database links
Registry Numbers Types Sources
122341-38-2 CAS Registry Number KEGG COMPOUND
122341-38-2 CAS Registry Number ChemIDplus
Last Modified
22 February 2017