CHEBI:180696 - 20β-dihydroprednisolone

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name 20β-dihydroprednisolone
ChEBI ID CHEBI:180696
ChEBI ASCII Name 20beta-dihydroprednisolone
Definition A glucocorticoid that is prednisolone in which the oxo group at position 20 has been reduced to the corresponding β-hydroxy group. It is a metabolite of prednisolone.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter R. Stephan
Supplier Information
Download Molfile XML SDF
Formula C21H30O5
Net Charge 0
Average Mass 362.466
Monoisotopic Mass 362.20932
InChI InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-18,22,24-26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,17-,18+,19-,20-,21-/m0/s1
InChIKey LCOVYWIXMAJCDS-FJWDNACWSA-N
SMILES [H][C@@]12CC[C@](O)([C@@H](O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
Metabolite of Species Details
Homo sapiens (NCBI:txid9606) Found in blood plasma (BTO:0000118). See: PubMed
Bos taurus (NCBI:txid9913) Found in urine (BTO:0001419). See: PubMed
Roles Classification
Biological Role(s): mammalian metabolite
Any animal metabolite produced during a metabolic reaction in mammals.
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
hormone
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
(via steroid hormone )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 20β-dihydroprednisolone (CHEBI:180696) has functional parent prednisolone (CHEBI:8378)
20β-dihydroprednisolone (CHEBI:180696) has role human metabolite (CHEBI:77746)
20β-dihydroprednisolone (CHEBI:180696) has role mammalian metabolite (CHEBI:75768)
20β-dihydroprednisolone (CHEBI:180696) is a 11β-hydroxy steroid (CHEBI:35346)
20β-dihydroprednisolone (CHEBI:180696) is a 17α-hydroxy steroid (CHEBI:35342)
20β-dihydroprednisolone (CHEBI:180696) is a 20-hydroxy steroid (CHEBI:36854)
20β-dihydroprednisolone (CHEBI:180696) is a 21-hydroxy steroid (CHEBI:35344)
20β-dihydroprednisolone (CHEBI:180696) is a 3-oxo-Δ1,Δ4-steroid (CHEBI:77166)
20β-dihydroprednisolone (CHEBI:180696) is a C21-steroid (CHEBI:61313)
20β-dihydroprednisolone (CHEBI:180696) is a glucocorticoid (CHEBI:24261)
IUPAC Name
(20S)-11β,17,20,21-tetrahydroxypregna-1,4-dien-3-one
Synonyms Sources
(11β,20S)-11,17,20,21-tetrahydroxypregna-1,4-dien-3-one ChemIDplus
(20S)-hydroxyprednisolone ChEBI
20(S)-hydroxy prednisolone ChEBI
20β-dihydro-PRED SUBMITTER
20β-hydroxyprednisolone ChemIDplus
prednisolone EP impurity G ChEBI
prednisolone impurity G ChemIDplus
Manual Xref Database
27524368 ChemSpider
View more database links
Registry Number Type Source
2299-46-9 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
23510304 PubMed citation Europe PMC
25267433 PubMed citation Europe PMC
25800201 PubMed citation SUBMITTER
28806969 PubMed citation Europe PMC
34081842 PubMed citation Europe PMC
898234 PubMed citation Europe PMC
9408088 PubMed citation Europe PMC
Last Modified
27 January 2022