CHEBI:197440 - Recombinant Tumor Necrosis Factor-alpha (human)
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Recombinant Tumor Necrosis Factor-alpha (human) |
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CHEBI:197440 |
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TNF-alpha is released from macrophages, monocytes, neutrophils, T-cells (principally CD4+), NK-cells and many transformed cell lines. Soluble homotrimeric TNF-alpha released from cells by proteolysis of the integral membrane precursor form of TNF-alpha. TNF-alpha binding to some TNF-alpha receptors induces apoptosis and depending on cell type, receptor expression, and signal transduction status can induce other responses. TNF-a is involved in the inflammatory response. |
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This entity has been manually annotated by a third party.
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Jonathan Muyskens
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Outgoing
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Recombinant Tumor Necrosis Factor-alpha (human)
(CHEBI:197440)
is a
organic molecular entity
(CHEBI:50860)
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Cachectin
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SUBMITTER
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Differentiation inducing factor (DIF)
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SUBMITTER
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Macrophage cytotoxic factor (MCF)
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SUBMITTER
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Necrosin
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SUBMITTER
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TNFSF2
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SUBMITTER
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Tumor necrosis factor-alpha
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SUBMITTER
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