CHEBI:170009 - favipiravir-RTP

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ChEBI Name favipiravir-RTP
ChEBI ID CHEBI:170009
Definition A nuceloside analogue in which the nucleobase is favipiravir. It is a RNA-dependent RNA polymerase inhibitor which exhibits anti-influenza and anti-coronaviral activities.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C10H15FN3O15P3
Net Charge 0
Average Mass 529.156
Monoisotopic Mass 528.97001
InChI InChI=1S/C10H15FN3O15P3/c11-4-1-14(9(18)5(13-4)8(12)17)10-7(16)6(15)3(27-10)2-26-31(22,23)29-32(24,25)28-30(19,20)21/h1,3,6-7,10,15-16H,2H2,(H2,12,17)(H,22,23)(H,24,25)(H2,19,20,21)/t3-,6-,7-,10-/m1/s1
InChIKey UUKPXXBDUCDZDA-KAFVXXCXSA-N
SMILES NC(=O)C1=NC(F)=CN([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C1=O
Roles Classification
Biological Role(s): anticoronaviral agent
Any antiviral agent which inhibits the activity of coronaviruses.
antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor
A DNA polymerase inhibitor that interferes with the action of a RNA-directed RNA polymerase (EC 2.7.7.48).
Application(s): antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing favipiravir-RTP (CHEBI:170009) has functional parent favipiravir (CHEBI:134722)
favipiravir-RTP (CHEBI:170009) has role anticoronaviral agent (CHEBI:149553)
favipiravir-RTP (CHEBI:170009) has role antiviral drug (CHEBI:36044)
favipiravir-RTP (CHEBI:170009) has role EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor (CHEBI:170010)
favipiravir-RTP (CHEBI:170009) is a nucleoside analogue (CHEBI:60783)
favipiravir-RTP (CHEBI:170009) is a organic triphosphate (CHEBI:62894)
favipiravir-RTP (CHEBI:170009) is a organofluorine compound (CHEBI:37143)
favipiravir-RTP (CHEBI:170009) is a primary carboxamide (CHEBI:140324)
favipiravir-RTP (CHEBI:170009) is a pyrazinone (CHEBI:167376)
IUPAC Name
6-fluoro-4-[5-O-(hydroxy{[hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl)-β-D-ribofuranosyl]-3-oxo-3,4-dihydropyrazine-2-carboxamide
Synonyms Sources
6-fluoro-3,4-dihydro-4-(5-O-(hydroxy((hydroxy(phosphonooxy)phosphinyl)oxy)phosphinyl)-β-D-ribofuranosyl)-3-oxo-2-pyrazinecarboxamide ChemIDplus
favipiravir riboside triphosphate ChemIDplus
T-705 ribosyl triphosphate ChEBI
T-705 RTP ChEBI
T-705-4-ribofuranosyl-5'-triphosphate ChEBI
T-705RTP ChemIDplus
Manual Xref Database
GE6 PDBeChem
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Registry Number Type Source
740790-94-7 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
15728892 PubMed citation Europe PMC
23917318 PubMed citation Europe PMC
24084488 PubMed citation Europe PMC
27120583 PubMed citation Europe PMC
28769016 PubMed citation Europe PMC
29906392 PubMed citation Europe PMC
33526596 PubMed citation Europe PMC
Last Modified
26 April 2021