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> Main
CHEBI:170009 - favipiravir-RTP
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ChEBI Name
favipiravir-RTP
ChEBI ID
CHEBI:170009
Definition
A nuceloside analogue in which the nucleobase is favipiravir. It is a RNA-dependent RNA polymerase inhibitor which exhibits anti-influenza and anti-coronaviral activities.
Stars
This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Molfile
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Formula
C10H15FN3O15P3
Net Charge
0
Average Mass
529.156
Monoisotopic Mass
528.97001
InChI
InChI=1S/C10H15FN3O15P3/c11-
4-
1-
14(9(18)
5(13-
4)
8(12)
17)
10-
7(16)
6(15)
3(27-
10)
2-
26-
31(22,23)
29-
32(24,25)
28-
30(19,20)
21/h1,3,6-
7,10,15-
16H,2H2,(H2,12,17)
(H,22,23)
(H,24,25)
(H2,19,20,21)
/t3-
,6-
,7-
,10-
/m1/s1
InChIKey
UUKPXXBDUCDZDA-KAFVXXCXSA-N
SMILES
NC(=O)C1=NC(F)=CN([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C1=O
Roles Classification
Biological Role
(s):
anticoronaviral agent
Any antiviral agent which inhibits the activity of coronaviruses.
antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor
A DNA polymerase inhibitor that interferes with the action of a RNA-directed RNA polymerase (EC 2.7.7.48).
Application
(s):
antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
favipiravir-RTP (
CHEBI:170009
)
has functional parent
favipiravir (
CHEBI:134722
)
favipiravir-RTP (
CHEBI:170009
)
has role
anticoronaviral agent (
CHEBI:149553
)
favipiravir-RTP (
CHEBI:170009
)
has role
antiviral drug (
CHEBI:36044
)
favipiravir-RTP (
CHEBI:170009
)
has role
EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor (
CHEBI:170010
)
favipiravir-RTP (
CHEBI:170009
)
is a
nucleoside analogue (
CHEBI:60783
)
favipiravir-RTP (
CHEBI:170009
)
is a
organic triphosphate (
CHEBI:62894
)
favipiravir-RTP (
CHEBI:170009
)
is a
organofluorine compound (
CHEBI:37143
)
favipiravir-RTP (
CHEBI:170009
)
is a
primary carboxamide (
CHEBI:140324
)
favipiravir-RTP (
CHEBI:170009
)
is a
pyrazinone (
CHEBI:167376
)
IUPAC Name
6-
fluoro-
4-
[5-
O
-
(hydroxy{[hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl)-
β-
D
-
ribofuranosyl]-
3-
oxo-
3,4-
dihydropyrazine-
2-
carboxamide
Synonyms
Sources
6-
fluoro-
3,4-
dihydro-
4-
(5-
O
-
(hydroxy((hydroxy(phosphonooxy)phosphinyl)oxy)phosphinyl)-
β-
D
-
ribofuranosyl)-
3-
oxo-
2-
pyrazinecarboxamide
ChemIDplus
favipiravir riboside triphosphate
ChemIDplus
T-705 ribosyl triphosphate
ChEBI
T-705 RTP
ChEBI
T-705-4-ribofuranosyl-5'-triphosphate
ChEBI
T-705RTP
ChemIDplus
Manual Xref
Database
GE6
PDBeChem
View more database links
Registry Number
Type
Source
740790-94-7
CAS Registry Number
ChemIDplus
Citations
Types
Sources
15728892
PubMed citation
Europe PMC
23917318
PubMed citation
Europe PMC
24084488
PubMed citation
Europe PMC
27120583
PubMed citation
Europe PMC
28769016
PubMed citation
Europe PMC
29906392
PubMed citation
Europe PMC
33526596
PubMed citation
Europe PMC
Last Modified
26 April 2021