CHEBI:90876 - Lonsurf

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ChEBI Name Lonsurf ChEBI ID CHEBI:90876 Definition A mixture composed of trifluridine, a nucleoside metabolic inhibitor, and tipiracil hydrochloride, a thymidine phosphorylase inhibitor. Lonsurf is used for treatment of advanced/relapsed unresectable colorectal cancer. Stars This entity has been manually annotated by the ChEBI Team. Roles Classification Biological Role(s): antifolate An antimetabolite that impairs the action of folic acids Application(s): antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. View more via ChEBI Ontology ChEBI Ontology Outgoing Lonsurf (CHEBI:90876) has part tipiracil hydrochloride (CHEBI:90877) Lonsurf (CHEBI:90876) has part trifluridine (CHEBI:75179) Lonsurf (CHEBI:90876) has role antifolate (CHEBI:73913) Lonsurf (CHEBI:90876) has role antineoplastic agent (CHEBI:35610) Lonsurf (CHEBI:90876) is a mixture (CHEBI:60004) Synonyms Sources TAS-102 ChEBI Trifluridine - tipiracil hydrochloride mixt KEGG DRUG Brand Name Source Lonsurf KEGG DRUG Manual Xref Database D10526 KEGG DRUG View more database links Citations Types Sources 25230742 PubMed citation Europe PMC 25596673 PubMed citation Europe PMC 25750295 PubMed citation Europe PMC 25776904 PubMed citation Europe PMC 25812794 PubMed citation Europe PMC 25970050 PubMed citation Europe PMC 26163340 PubMed citation Europe PMC 26197742 PubMed citation Europe PMC 26254349 PubMed citation Europe PMC 26370544 PubMed citation Europe PMC 26428513 PubMed citation Europe PMC 26489584 PubMed citation Europe PMC 26509228 PubMed citation Europe PMC 26535019 PubMed citation Europe PMC 26557901 PubMed citation Europe PMC 26609205 PubMed citation Europe PMC 26616466 PubMed citation Europe PMC 26677869 PubMed citation Europe PMC 26722024 PubMed citation Europe PMC 26723516 PubMed citation Europe PMC Last Modified 08 January 2016