InChI=1S/C27H41F2N5O/c1- 7- 8- 23(32- 20- 10- 9- 18- 11- 19(28) 12- 22(29) 21(18) 13- 20) 25(35) 33- 24- 14- 34(17- 31- 24) 27(5,6) 16- 30- 15- 26(2,3) 4/h11- 12,14,17,20,23,30,32H,7- 10,13,15- 16H2,1- 6H3,(H,33,35) /t20- ,23- /m0/s1 |
VFCRKLWBYMDAED-REWPJTCUSA-N |
CCC[C@H](N[C@H]1CCC2=CC(F)=CC(F)=C2C1)C(=O)NC1=CN(C=N1)C(C)(C)CNCC(C)(C)C |
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Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
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gamma-secretase modulator
A modulator of gamma-secretase, one of the three endopeptidases that are specific for amyloid protein precursor and which have been identified based upon the region of the amyloid protein precursor which they cleave.
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antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
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View more via ChEBI Ontology
N2- [(2S)- 6,8- difluoro- 1,2,3,4- tetrahydronaphthalen- 2- yl]- N- (1- {1- [(2,2- dimethylpropyl)amino]- 2- methylpropan- 2- yl}- 1H- imidazol- 4- yl)- L- norvalinamide
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nirogacéstat
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WHO MedNet
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nirogacestat
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WHO MedNet
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nirogacestat
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WHO MedNet
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nirogacestatum
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WHO MedNet
|
(2S)- 2- {[(2S)- 6,8- difluoro- 1,2,3,4- tetrahydronaphthalen- 2- yl]amino}- N- (1- {1- [(2,2- dimethylpropyl)amino]- 2- methylpropan- 2- yl}- 1H- imidazol- 4- yl)pentanamide
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IUPAC
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(S)- 2- ((S)- 5,7- difluoro- 1,2,3,4- tetrahydronaphthalen- 3- ylamino)- N- (1- (2- methyl- 1- (neopentylamino)propan- 2- yl)- 1H- imidazol- 4- yl)pentanamide
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ChEBI
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PF-03084014
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DrugBank
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PF-3084014
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DrugBank
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1290543-63-3
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CAS Registry Number
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KEGG DRUG
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20363853
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22806875
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