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> Main
CHEBI:81467 - 7α-hydroxypregnenolone
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ChEBI Ontology
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ChEBI Name
7α-hydroxypregnenolone
ChEBI ID
CHEBI:81467
ChEBI ASCII Name
7alpha-hydroxypregnenolone
Definition
A 20-oxo steroid that is pregnenolone carrying an additional hydroxy substituent at the 7α-position.
Stars
This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula
C21H32O3
Net Charge
0
Average Mass
332.478
Monoisotopic Mass
332.23514
InChI
InChI=1S/C21H32O3/c1-
12(22)
15-
4-
5-
16-
19-
17(7-
9-
21(15,16)
3)
20(2)
8-
6-
14(23)
10-
13(20)
11-
18(19)
24/h11,14-
19,23-
24H,4-
10H2,1-
3H3/t14-
,15+,16-
,17-
,18+,19-
,20-
,21+/m0/s1
InChIKey
UEWNVBNIVGLQPG-XXHSLLPRSA-N
SMILES
C1[C@@]2([C@]3(CC[C@]4(C)[C@@H](C(C)=O)CC[C@]4([C@@]3([C@@H](C=C2C[C@H](C1)O)O)[H])[H])[H])C
Metabolite of Species
Details
Petromyzon marinus
(NCBI:txid7757)
See:
PubMed
Ictalurus punctatus
(NCBI:txid7998)
See:
PubMed
Oncorhynchus mykiss
(NCBI:txid8022)
See:
PubMed
Cynops pyrrhogaster
(NCBI:txid8330)
See:
PubMed
Coturnix japonica
(NCBI:txid93934)
See:
PubMed
Roles Classification
Biological Role
(s):
rat metabolite
Any mammalian metabolite produced during a metabolic reaction in rat (
Rattus norvegicus
).
marine metabolite
Any metabolite produced during a metabolic reaction in marine macro- and microorganisms.
dopaminergic agent
A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons.
Application
(s):
nootropic agent
Any compound that improves mental functions such as cognition, memory, intelligence, motivation, attention, and concentration.
dopaminergic agent
A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
7α-hydroxypregnenolone (
CHEBI:81467
)
has functional parent
pregnenolone (
CHEBI:16581
)
7α-hydroxypregnenolone (
CHEBI:81467
)
has role
dopaminergic agent (
CHEBI:48560
)
7α-hydroxypregnenolone (
CHEBI:81467
)
has role
marine metabolite (
CHEBI:76507
)
7α-hydroxypregnenolone (
CHEBI:81467
)
has role
nootropic agent (
CHEBI:66980
)
7α-hydroxypregnenolone (
CHEBI:81467
)
has role
rat metabolite (
CHEBI:86264
)
7α-hydroxypregnenolone (
CHEBI:81467
)
is a
20-oxo steroid (
CHEBI:36885
)
7α-hydroxypregnenolone (
CHEBI:81467
)
is a
3β-hydroxy-Δ
5
-steroid (
CHEBI:1722
)
7α-hydroxypregnenolone (
CHEBI:81467
)
is a
7α-hydroxy steroid (
CHEBI:36843
)
7α-hydroxypregnenolone (
CHEBI:81467
)
is a
C
21
-steroid (
CHEBI:61313
)
7α-hydroxypregnenolone (
CHEBI:81467
)
is enantiomer of
7β-hydroxypregnenolone (
CHEBI:183806
)
Incoming
7β-hydroxypregnenolone (
CHEBI:183806
)
is enantiomer of
7α-hydroxypregnenolone (
CHEBI:81467
)
IUPAC Name
3β,7α-dihydroxypregn-5-en-20-one
Synonyms
Sources
(3β,7α)-3,7-dihydroxypregn-5-en-20-one
IUPAC
3beta,7alpha-Dihydroxy-5-pregnen-20-one
KEGG COMPOUND
7α-hydroxypregnenolone
UniProt
Manual Xrefs
Databases
C18038
KEGG COMPOUND
HMDB0060424
HMDB
View more database links
Registry Number
Type
Source
3157694
Reaxys Registry Number
Reaxys
Citations
Types
Sources
12714005
PubMed citation
Europe PMC
12927902
PubMed citation
Europe PMC
15193266
PubMed citation
Europe PMC
15569930
PubMed citation
Europe PMC
16902960
PubMed citation
Europe PMC
17065445
PubMed citation
Europe PMC
18305249
PubMed citation
Europe PMC
19362555
PubMed citation
Europe PMC
19456338
PubMed citation
Europe PMC
19456352
PubMed citation
Europe PMC
19456373
PubMed citation
Europe PMC
19456382
PubMed citation
Europe PMC
20138182
PubMed citation
Europe PMC
20219980
PubMed citation
Europe PMC
9679086
PubMed citation
Europe PMC
Last Modified
11 April 2018