6-azauridine 5'-monophosphate(2-) (CHEBI:147401)

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ChEBI Name	6-azauridine 5'-monophosphate(2−)

ChEBI ID	CHEBI:147401

ChEBI ASCII Name	6-azauridine 5'-monophosphate(2-)

Definition	An organophosphate oxoanion obtained by deprotonation of the phosphate OH groups of 6-azauridine 5'-monophosphate. Major species at pH 7.3.

Stars	This entity has been manually annotated by the ChEBI Team.

Submitter	Anne Morgat

Supplier Information

Download	Molfile XML SDF

Formula

C8H10N3O9P

Net Charge

-2

Average Mass

323.155

Monoisotopic Mass

323.01656

InChI

InChI=1S/C8H12N3O9P/c12-4-1-9-11(8(15)10-4)7-6(14)5(13)3(20-7)2-19-21(16,17)18/h1,3,5-7,13-14H,2H2,(H,10,12,15)(H2,16,17,18)/p-2/t3-,5-,6-,7-/m1/s1

InChIKey

LRVZOSYMNMNQFR-SHUUEZRQSA-L

SMILES

[C@H]1(O[C@H](COP([O-])(=O)[O-])[C@H]([C@H]1O)O)N2C(NC(C=N2)=O)=O

Roles Classification
Biological Role(s):	EC 4.1.1.23 (orotidine-5'-phosphate decarboxylase) inhibitor Any EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of orotidine-5'-phosphate decarboxylase (EC 4.1.1.23).

Application(s):	antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology
Outgoing	6-azauridine 5'-monophosphate(2−) (CHEBI:147401) has role antineoplastic agent (CHEBI:35610) 6-azauridine 5'-monophosphate(2−) (CHEBI:147401) has role EC 4.1.1.23 (orotidine-5'-phosphate decarboxylase) inhibitor (CHEBI:90285) 6-azauridine 5'-monophosphate(2−) (CHEBI:147401) is a organophosphate oxoanion (CHEBI:58945) 6-azauridine 5'-monophosphate(2−) (CHEBI:147401) is conjugate base of 6-azauridine 5'-monophosphate (CHEBI:46319)

Incoming	6-azauridine 5'-monophosphate (CHEBI:46319) is conjugate acid of 6-azauridine 5'-monophosphate(2−) (CHEBI:147401)

IUPAC Name

2-(5-O-phosphonato-β-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione

Synonyms	Sources
6-aza UMP(2−)	ChEBI
6-azauridine 5'-phosphate	UniProt
[(2R,3S,4R,5R)-5-(3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl phosphate	IUPAC

Last Modified

04 May 2020