|
(−)-antofine |
|
CHEBI:143911 |
|
(-)-antofine |
|
An organic heteropentacyclic compound that is (13aR)-9,11,12,13,13a,14-hexahydrodibenzo[f,h]pyrrolo[1,2-b]isoquinoline substituted at positions 2, 3 and 6 by methoxy groups. It is an alkaloid produced by relatives of the milkweed family and exhibits antiviral, anti-inflammatory, antiadipogenic and antitumorigenic activities. |
|
This entity has been manually annotated by the ChEBI Team.
|
|
Rob Nash
|
|
|
|
Molfile
XML
SDF
|
|
|
|
InChI=1S/C23H25NO3/c1-25-15-6-7-16-18(10-15)20-12-23(27-3)22(26-2)11-19(20)17-9-14-5-4-8-24(14)13-21(16)17/h6-7,10-12,14H,4-5,8-9,13H2,1-3H3/t14-/m1/s1 |
NCVWJDISIZHFQS-CQSZACIVSA-N |
C=1C2=C(C=C(C1OC)OC)C=3C=C(C=CC3C4=C2C[C@]5(CCCN5C4)[H])OC |
|
Cryptocarya phyllostemon
(IPNI:895989-1)
|
See:
DOI
|
Cynanchum vincetoxicum
(NCBI:txid141524)
|
See:
PubMed
|
Vincetoxicum rossicum
(NCBI:txid429301)
|
See:
PubMed
|
Vincetoxicum nigrum
(NCBI:txid63502)
|
See:
PubMed
|
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
phytotoxin
Any toxin produced by a plant.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via alkaloid antibiotic )
antiviral agent
A substance that destroys or inhibits replication of viruses.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
|
|
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
anti-inflammatory agent
Any compound that has anti-inflammatory effects.
angiogenesis inhibitor
An agent and endogenous substances that antagonize or inhibit the development of new blood vessels.
|
|
View more via ChEBI Ontology
(13aR)-2,3,6-trimethoxy-9,11,12,13,13a,14-hexahydrodibenzo[f,h]pyrrolo[1,2-b]isoquinoline
|
(−)-antofine
|
KNApSAcK
|
(13aR)-2,3,6-trimethoxy-9,11,12,13,13a,14-hexahydrophenanthro[9,10-f]indolizine
|
SUBMITTER
|
(R)-(−)-antofine
|
ChEBI
|
(R)-2,3,6-trimethoxy-9,11,12,13,13a,14-hexahydrodibenzo[f,h]pyrrolo[1,2-b]isoquinoline
|
ChEBI
|
(R)-antofine
|
ChEBI
|
2,3,6-trimethoxy-9,10,11,12,12a,13-hexahydro-9a-aza-cyclopenta[b]triphenylene
|
ChEBI
|
2,3,6-trimethoxy-9,11,12,13,13a,14-hexahydrodibenzo[f,h]pyrrolo[1,2-b]isoquinoline
|
SUBMITTER
|
7-demethoxytylophorine
|
ChEBI
|
9,11,12,13,13a,14-hexahydro-2,3,6-trimethoxydibenzo[f,h]pyrrolo[1,2-b]isoquinoline
|
ChEBI
|
antofine
|
ChEBI
|
32671-82-2
|
CAS Registry Number
|
KNApSAcK
|
12350151
|
PubMed citation
|
SUBMITTER
|
12868894
|
PubMed citation
|
SUBMITTER
|
17049857
|
PubMed citation
|
SUBMITTER
|
20151387
|
PubMed citation
|
SUBMITTER
|
21739223
|
PubMed citation
|
Europe PMC
|
22753104
|
PubMed citation
|
SUBMITTER
|
22880628
|
PubMed citation
|
SUBMITTER
|
24934681
|
PubMed citation
|
SUBMITTER
|
28666888
|
PubMed citation
|
Europe PMC
|
28805975
|
PubMed citation
|
SUBMITTER
|
30691129
|
PubMed citation
|
Europe PMC
|
31186319
|
PubMed citation
|
Europe PMC
|
|