CHEBI:229539 - durlobactam

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ChEBI Name durlobactam
ChEBI ID CHEBI:229539
Definition A member of the class of azabicycloalkanes that is (1R,2S,5R)-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-ene-2-carboxamide in which the amino hydrogen at position 6 is replaced by a sulfooxy group.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C8H11N3O6S
Net Charge 0
Average Mass 277.250
Monoisotopic Mass 277.03686
InChI InChI=1S/C8H11N3O6S/c1-4-2-5-3-10(6(4)7(9)12)8(13)11(5)17-18(14,15)16/h2,5-6H,3H2,1H3,(H2,9,12)(H,14,15,16)/t5-,6+/m1/s1
InChIKey BISPBXFUKNXOQY-RITPCOANSA-N
SMILES CC1=C[C@@H]2C[N@]([C@@H]1C(N)=O)C(=O)N2OS(O)(=O)=O
Roles Classification
Biological Role(s): EC 3.5.2.6 (beta-lactamase) inhibitor
An EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor that interferes with the action of beta-lactamase (EC 3.5.2.6).
antibacterial drug
A drug used to treat or prevent bacterial infections.
Application(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing durlobactam (CHEBI:229539) has role antibacterial drug (CHEBI:36047)
durlobactam (CHEBI:229539) has role EC 3.5.2.6 (β-lactamase) inhibitor (CHEBI:35625)
durlobactam (CHEBI:229539) is a azabicycloalkane (CHEBI:38295)
durlobactam (CHEBI:229539) is a hydroxylamine O-sulfonic acid (CHEBI:38025)
durlobactam (CHEBI:229539) is a monocarboxylic acid amide (CHEBI:29347)
durlobactam (CHEBI:229539) is a primary carboxamide (CHEBI:140324)
durlobactam (CHEBI:229539) is conjugate acid of durlobactam(1−) (CHEBI:229545)
Incoming durlobactam(1−) (CHEBI:229545) is conjugate base of durlobactam (CHEBI:229539)
IUPAC Name
(1R,2S,5R)-3-methyl-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]oct-3-ene-2-carboxamide
INNs Sources
durlobactam WHO MedNet
durlobactam WHO MedNet
durlobactam WHO MedNet
durlobactamum WHO MedNet
Synonyms Sources
ETX 2514 DrugBank
ETX-2514 DrugBank
ETX2514 DrugBank
Manual Xrefs Databases
D11591 KEGG DRUG
DB16704 DrugBank
Durlobactam Wikipedia
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Registry Number Type Source
1467829-71-5 CAS Registry Number KEGG DRUG
Citations Waiting for Citations Types Sources
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Last Modified
06 February 2024