CHEBI:191178 - goralatide

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ChEBI Name goralatide
ChEBI ID CHEBI:191178
Definition A tetrapeptide that is Ser-Asp-Lys-Pro in which the N-terminal amino group carries an acetyl group. It is selective inhibitor of primitive haematopoietic cell proliferation and exhibits anti-inflammatory, anti-fibrotic, and pro-angiogenic properties.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C20H33N5O9
Net Charge 0
Average Mass 487.510
Monoisotopic Mass 487.22783
InChI InChI=1S/C20H33N5O9/c1-11(27)22-14(10-26)18(31)24-13(9-16(28)29)17(30)23-12(5-2-3-7-21)19(32)25-8-4-6-15(25)20(33)34/h12-15,26H,2-10,21H2,1H3,(H,22,27)(H,23,30)(H,24,31)(H,28,29)(H,33,34)/t12-,13-,14-,15-/m0/s1
InChIKey HJDRXEQUFWLOGJ-AJNGGQMLSA-N
SMILES CC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(O)=O
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
pro-angiogenic agent
Any compound that promotes the growth of new blood vessels from pre-existing vessels.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing goralatide (CHEBI:191178) has functional parent Ser-Asp-Lys-Pro (CHEBI:191177)
goralatide (CHEBI:191178) has role anti-inflammatory agent (CHEBI:67079)
goralatide (CHEBI:191178) has role pro-angiogenic agent (CHEBI:72571)
goralatide (CHEBI:191178) is a tetrapeptide (CHEBI:48030)
goralatide (CHEBI:191178) is conjugate acid of goralatide(1−) (CHEBI:190701)
Incoming goralatide(1−) (CHEBI:190701) is conjugate base of goralatide (CHEBI:191178)
IUPAC Name
N-acetyl-L-seryl-L-α-aspartyl-L-lysyl-L-proline
INNs Sources
goralatida WHO MedNet
goralatide WHO MedNet
goralatide WHO MedNet
goralatidum WHO MedNet
Synonyms Sources
Ac-SDKP HMDB
Ac-Ser-Asp-Lys-Pro ChEBI
Ac-Ser-Asp-Lys-Pro-OH HMDB
acetyl-N-Ser-Asp-Lys-Pro ChEBI
acetyl-seryl-aspartyl-lysyl-proline ChEBI
AcSDKP ChEBI
N-acetyl-L-Ser-L-Asp-L-Lys-L-Pro ChEBI
N-acetyl-Ser-Asp-Lys-Pro ChEBI
N-acetyl-seryl-aspartyl-lysyl-proline ChEBI
NAcSerAspLysPro ChEBI
seraspenide ChEBI
Manual Xrefs Databases
59343 ChemSpider
HMDB0062552 HMDB
View more database links
Registry Number Type Source
120081-14-3 CAS Registry Number ChemIDplus
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Last Modified
14 April 2022