oxiconazole (CHEBI:7825)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	oxiconazole

ChEBI ID	CHEBI:7825

Definition	An oxime O-ether that is the 2,4-dichlorobenzyl ether of the oxime obtained by formal condensation of hydroxylamine with the carbonyl group of acetopnenone in which the phenyl group is substituted by chlorines at positions 2 and 4, and in which one of the hydrogens of the methyl group is replaced by a 1H-imidazol-1-yl group. An antifungal agent, it is used (generally as the nitrate salt) in creams and powders for the topical treatment of fungal skin infections.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Wikipedia	License

Read full article at Wikipedia

Formula

C18H13Cl4N3O

Net Charge

Average Mass

429.12700

Monoisotopic Mass

426.98127

InChI

InChI=1S/C18H13Cl4N3O/c19-13-2-1-12(16(21)7-13)10-26-24-18(9-25-6-5-23-11-25)15-4-3-14(20)8-17(15)22/h1-8,11H,9-10H2/b24-18+

InChIKey

QRJJEGAJXVEBNE-HKOYGPOVSA-N

SMILES

Clc1ccc(CO\N=C(/Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1

Roles Classification
Biological Role(s):	antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. (via imidazole antifungal drug ) (via conazole antifungal drug ) antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. (via imidazole antifungal agent ) (via conazole antifungal agent ) ergosterol biosynthesis inhibitor Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol. (via conazole antifungal agent )

Application(s):	antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. (via imidazole antifungal drug ) (via conazole antifungal drug )

ChEBI Ontology
Outgoing	oxiconazole (CHEBI:7825) has role antiinfective agent (CHEBI:35441) oxiconazole (CHEBI:7825) is a conazole antifungal drug (CHEBI:87071) oxiconazole (CHEBI:7825) is a dichlorobenzene (CHEBI:23697) oxiconazole (CHEBI:7825) is a imidazole antifungal drug (CHEBI:87069) oxiconazole (CHEBI:7825) is a imidazoles (CHEBI:24780) oxiconazole (CHEBI:7825) is a oxime O-ether (CHEBI:36816) oxiconazole (CHEBI:7825) is conjugate base of oxiconazole(1+) (CHEBI:77698)

Incoming	oxiconazole(1+) (CHEBI:77698) is conjugate acid of oxiconazole (CHEBI:7825)

IUPAC Name

(1Z)-N-[(2,4-dichlorobenzyl)oxy]-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanimine

Synonyms	Sources
2',4'-Dichloro-2-imidazol-1-ylacetophenone (Z)-[O-(2,4-dichlorobenzyl)oxime]	ChemIDplus
Ro 13-8996	ChemIDplus

Last Modified

22 February 2017