salvigenin (CHEBI:192703)

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ChEBI Name	salvigenin

ChEBI ID	CHEBI:192703

Definition	A trimethoxyflavone that is scutellarein in which the hydroxy groups at positions 4', 6, and 7 are replaced by methoxy groups.

Stars	This entity has been manually annotated by the ChEBI Team.

Submitter	Kristian Axelsen

Supplier Information

Download	Molfile XML SDF

Formula

C18H16O6

Net Charge

Average Mass

328.320

Monoisotopic Mass

328.09469

InChI

InChI=1S/C18H16O6/c1-21-11-6-4-10(5-7-11)13-8-12(19)16-14(24-13)9-15(22-2)18(23-3)17(16)20/h4-9,20H,1-3H3

InChIKey

QCDYOIZVELGOLZ-UHFFFAOYSA-N

SMILES

COC1=CC=C(C=C1)C1=CC(=O)C2=C(O1)C=C(OC)C(OC)=C2O

Metabolite of Species	Details
Astragalus brachystachys (IPNI:476523-1)	See: PubMed
Teucrium flavum subsp. glaucum (NCBI:txid1046082)	See: PubMed
Withania somnifera (NCBI:txid126910)	See: PubMed
Hyssopus cuspidatus (NCBI:txid1439902)	See: PubMed
Salvia judaica (NCBI:txid1520030)	Found in aerial part (BTO:0001658). See: PubMed
Salvia atropatana (NCBI:txid1685711)	Found in aerial part (BTO:0001658). See: PubMed
Salvia russellii (NCBI:txid1933755)	Found in aerial part (BTO:0001658). See: PubMed
Ocimum gratissimum (NCBI:txid204144)	See: PubMed
Salvia yangii (NCBI:txid268885)	Found in leaf (BTO:0000713). Species also known as Perovskia atriplicifolia. See: PubMed
Achillea wilhelmsii (NCBI:txid282771)	See: PubMed
Tanacetum canescens (NCBI:txid301878)	Found in whole plant (BTO:0001461). See: PubMed
Ocimum basilicum (NCBI:txid39350)	See: PubMed

Roles Classification
Biological Role(s):	autophagy inducer Any compound that induces the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell). apoptosis inhibitor Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms. immunomodulator Biologically active substance whose activity affects or plays a role in the functioning of the immune system. plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.

Application(s):	antilipemic drug A substance used to treat hyperlipidemia (an excess of lipids in the blood). immunomodulator Biologically active substance whose activity affects or plays a role in the functioning of the immune system. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. hypoglycemic agent A drug which lowers the blood glucose level.

ChEBI Ontology
Outgoing	salvigenin (CHEBI:192703) has functional parent scutellarein (CHEBI:9062) salvigenin (CHEBI:192703) has role antilipemic drug (CHEBI:35679) salvigenin (CHEBI:192703) has role antineoplastic agent (CHEBI:35610) salvigenin (CHEBI:192703) has role apoptosis inhibitor (CHEBI:68494) salvigenin (CHEBI:192703) has role autophagy inducer (CHEBI:138880) salvigenin (CHEBI:192703) has role hypoglycemic agent (CHEBI:35526) salvigenin (CHEBI:192703) has role immunomodulator (CHEBI:50846) salvigenin (CHEBI:192703) has role neuroprotective agent (CHEBI:63726) salvigenin (CHEBI:192703) has role plant metabolite (CHEBI:76924) salvigenin (CHEBI:192703) is a monohydroxyflavone (CHEBI:38687) salvigenin (CHEBI:192703) is a trimethoxyflavone (CHEBI:27124)

IUPAC Name

5-hydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one

Synonyms	Sources
5-hydroxy-4',6,7-trimethoxyflavone	MetaCyc
5-hydroxy-6,7,4'-trimethoxy-flavone	ChemIDplus
5-hydroxy-6,7,4'-trimethoxyflavone	ChemIDplus
5-hydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one	IUPAC
7-O-methylpectolinarigenin	MetaCyc
psathyrotin	MetaCyc
salvigenin	UniProt

Last Modified

26 August 2022