gravacridonediol (CHEBI:195185)

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ChEBI Name	gravacridonediol

ChEBI ID	CHEBI:195185

Definition	An acridone derivative with formula C₁₉H₁₉NO₅. It is isolated from the roots of Ruta graveolens and Thamnosma rhodesica.

Stars	This entity has been manually annotated by the ChEBI Team.

Submitter	Mark Williams

Supplier Information

Download	Molfile XML SDF

Formula

C19H19NO5

Net Charge

Average Mass

341.363

Monoisotopic Mass

341.12632

InChI

InChI=1S/C19H19NO5/c1-19(24,9-21)15-7-11-14(25-15)8-13(22)16-17(11)20(2)12-6-4-3-5-10(12)18(16)23/h3-6,8,15,21-22,24H,7,9H2,1-2H3

InChIKey

RQAGSTDFTGSIGB-UHFFFAOYSA-N

SMILES

CN1C2=CC=CC=C2C(=O)C2=C1C1=C(OC(C1)C(C)(O)CO)C=C2O

Metabolite of Species	Details
Ruta graveolens (NCBI:txid37565)	Found in Root (BTO:0001188). See: PubMed
Thamnosma rhodesica (NCBI:txid675746)	Found in Root (BTO:0001188). See: PubMed

Roles Classification
Biological Role(s):	antileishmanial agent An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania. plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. (via alkaloid )

Application(s):	antileishmanial agent An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania.

ChEBI Ontology
Outgoing	gravacridonediol (CHEBI:195185) has role antileishmanial agent (CHEBI:70868) gravacridonediol (CHEBI:195185) has role plant metabolite (CHEBI:76924) gravacridonediol (CHEBI:195185) is a acridone derivatives (CHEBI:61878) gravacridonediol (CHEBI:195185) is a alkaloid (CHEBI:22315) gravacridonediol (CHEBI:195185) is a cyclic ether (CHEBI:37407) gravacridonediol (CHEBI:195185) is a organic heterotetracyclic compound (CHEBI:38163) gravacridonediol (CHEBI:195185) is a primary alcohol (CHEBI:15734) gravacridonediol (CHEBI:195185) is a tertiary alcohol (CHEBI:26878) gravacridonediol (CHEBI:195185) is a triol (CHEBI:27136)

IUPAC Name

2-(1,2-dihydroxypropan-2-yl)-5-hydroxy-11-methyl-1,11-dihydrofuro[2,3-c]acridin-6(2H)-one

Synonyms	Sources
2-(1,2-dihydroxy-1-methylethyl)-1,11-dihydro-5-hydroxy-11-methylfuro[2,3-c]acridin-6(2H)-one	ChEBI
2-(1,2-dihydroxypropan-2-yl)-5-hydroxy-11-methyl-1,2-dihydrouro[2,3-c]acridin-6-one	SUBMITTER
gravacridondiol	ChEBI

Registry Number	Type	Source
37551-75-0	CAS Registry Number	KNApSAcK

Last Modified

02 June 2023