CHEBI:65889 - eurysterol B

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ChEBI Name eurysterol B
ChEBI ID CHEBI:65889
Definition An organic sodium salt that is monosodium salt of eurysterol B sulfonic acid. Isolated from an undescribed marine sponge of the genus Euryspongia collected in Palau, it is cytotoxic and exhibits antifungal activity against both amphotericin B-resistant and wild-type strains of Candida albicans.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C27H43NaO7S
Net Charge 0
Average Mass 534.68100
Monoisotopic Mass 534.26272
InChI InChI=1S/C27H44O7S.Na/c1-17(2)6-5-7-18(3)20-8-9-21-24(20,4)12-11-22-25-13-10-19(34-35(30,31)32)14-27(25,29)23(28)15-26(21,22)33-16-25;/h5,7,17-23,28-29H,6,8-16H2,1-4H3,(H,30,31,32);/q;+1/p-1/b7-5+;/t18-,19+,20-,21-,22-,23-,24-,25+,26-,27+;/m1./s1
InChIKey OZULCLLLPIEFBL-FUPZROSBSA-M
SMILES [Na+].[H][C@@]1(CC[C@]2([H])[C@]1(C)CC[C@]1([H])[C@@]34CC[C@@H](C[C@]3(O)[C@H](O)C[C@@]21OC4)OS([O-])(=O)=O)[C@H](C)\C=C\CC(C)C
Metabolite of Species Details
Euryspongia (WORMS:164976) See: PubMed
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
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ChEBI Ontology
Outgoing eurysterol B (CHEBI:65889) has parent hydride 5α-cholestane (CHEBI:35515)
eurysterol B (CHEBI:65889) has part eurysterol B(1−) (CHEBI:68593)
eurysterol B (CHEBI:65889) has role antifungal agent (CHEBI:35718)
eurysterol B (CHEBI:65889) has role antineoplastic agent (CHEBI:35610)
eurysterol B (CHEBI:65889) has role metabolite (CHEBI:25212)
eurysterol B (CHEBI:65889) is a organic sodium salt (CHEBI:38700)
IUPAC Name
sodium(3β,5α,6β,22E)-5,6-dihydroxy-8,19-epoxycholest-22-en-3-yl sulfate
Synonym Source
sodium (22E)-5α-cholest-22-en-8,19-epoxy-3β,5,6β-triol-3-sulphate ChEBI
Registry Number Type Source
11166279 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
17378608 PubMed citation Europe PMC
Last Modified
04 October 2012