baicalein(1-) (CHEBI:78324)

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ChEBI Name	baicalein(1−)

ChEBI ID	CHEBI:78324

ChEBI ASCII Name	baicalein(1-)

Definition	A flavonoid oxoanion obtained by deprotonation of the hydroxy group at position 7 of baicalein. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.).

Stars	This entity has been manually annotated by the ChEBI Team.

Submitter	Anne Morgat

Supplier Information

Download	Molfile XML SDF

Formula

C15H9O5

Net Charge

-1

Average Mass

269.22950

Monoisotopic Mass

269.04555

InChI

InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H/p-1

InChIKey

FXNFHKRTJBSTCS-UHFFFAOYSA-M

SMILES

Oc1c([O-])cc2oc(cc(=O)c2c1O)-c1ccccc1

Roles Classification
Chemical Role(s):	antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. radical scavenger A role played by a substance that can react readily with, and thereby eliminate, radicals.

Biological Role(s):	EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor A lipoxygenase inhibitor that interferes with the action of arachidonate 12-lipoxygenase (EC 1.13.11.31). EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor A lipoxygenase inhibitor that interferes with the action of arachidonate 15-lipoxygenase (EC 1.13.11.33). EC 3.4.21.26 (prolyl oligopeptidase) inhibitor Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26). hormone antagonist A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. prostaglandin antagonist A compound that inhibits the action of prostaglandins. metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.

Application(s):	hormone antagonist A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. prostaglandin antagonist A compound that inhibits the action of prostaglandins.

ChEBI Ontology
Outgoing	baicalein(1−) (CHEBI:78324) has role antioxidant (CHEBI:22586) baicalein(1−) (CHEBI:78324) has role EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor (CHEBI:64995) baicalein(1−) (CHEBI:78324) has role EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor (CHEBI:64996) baicalein(1−) (CHEBI:78324) has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor (CHEBI:76779) baicalein(1−) (CHEBI:78324) has role hormone antagonist (CHEBI:49020) baicalein(1−) (CHEBI:78324) has role metabolite (CHEBI:25212) baicalein(1−) (CHEBI:78324) has role prostaglandin antagonist (CHEBI:49023) baicalein(1−) (CHEBI:78324) has role radical scavenger (CHEBI:48578) baicalein(1−) (CHEBI:78324) is a flavonoid oxoanion (CHEBI:60038) baicalein(1−) (CHEBI:78324) is conjugate base of baicalein (CHEBI:2979)

Incoming	baicalein (CHEBI:2979) is conjugate acid of baicalein(1−) (CHEBI:78324)

IUPAC Name

5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-olate

Synonym	Source
baicalein	UniProt

Last Modified

24 June 2014